Award Data

DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

Firebird will deliver a hand-held CLIA-waivable battery-powered device that will allow point-of-need detection of norovirus RNA, with a fluorescence readout excited by a battery-powered LED. The readout can be interpreted at the point-of-need, or transmitted by cell phone to a distant site. This devise is possible only through the application of five technologies to which Firebird has exclusive ac ...

Many military casualties survive the first few days of burn and trauma resuscitation and surgeries only to fall victim to an infection and sepsis. Intensive care for these casualties is complex, requires treatment of systemic and often multiple organ systems at a time and is highly error prone. Evidence-based best practices are published, but yet not implemented in step by step detail at the bedsi ...

The rapid ascent and adoption of social media as the dominant form of communication has led to significant analysis challenges. In particular, there is a gap in theoretically informed methods to analyze data mined and collected from social media. One primary cause of this gap is the lack of fusing structural sources of information (e.g. social network topology) with non-structural sources (message ...

This proposal addresses the need for a portable closed loop burn resuscitation system to optimize fluid therapy, automate medical caretaker tasks, and record and communicate resuscitation data. Patient care can be further optimized by the integration of a closed looped ventilator into the platform. The proposed system will be capable of intelligently determining fluid therapy parameters, minimi ...

Burns represent 5-10% of overall military casualties. Burn resuscitation requires large volume and carries the risk of severe complications or mortality resulting from under-resuscitation or over-resuscitation with severe edema and associated conditions. Traditional fluid therapy requires hourly adjustment as the burn pathophysiology changes during the resuscitation phase. Casualty evacuations (CA ...

In this STTR program, Structured Materials Industries, Inc. (SMI) and partners will develop hardware and process technology to deposit uniform films of piezoelectric PbZrxTi1-xO3, on substrates with complex 3-dimensional topography. Piezoelectric PbZrxTi1-xO3 films are a critical technology for advanced Micro Electro Mechanical System (MEMS), to provide low power actuation in nanoscale devices. ...

Advanced infrared imaging (night vision) equipment is a critical component of the US military's tactical capability. The development of third-generation, multi-wavelength infrared focal-plane arrays (FPAs) promises to enhance the superiority of the US mil

DESCRIPTION provided by applicant With the advent of rapid bench top sequencers such as the PGM and MiSeq the potential to transform cancer diagnosis and patient care is great Although sequencing instrumentation has become relatively affordable the need for NGS data analysis and interpretation still remains a big hurdle to the adoption of NGS based assays for many research and clinical labor ...

DESCRIPTION provided by applicant B cell lymphoma is cancer of B lymphocytes and accounts for more than deaths in the U S each year While many patients respond to currently available therapy there is a high rate of cancer relapse and inability for the patients o tolerate chemotherapy Thus there is a significant need to make available to these patients newer therapies that are more e ...