Award Data

DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

DESCRIPTION provided by applicant With the advent of rapid bench top sequencers such as the PGM and MiSeq the potential to transform cancer diagnosis and patient care is great Although sequencing instrumentation has become relatively affordable the need for NGS data analysis and interpretation still remains a big hurdle to the adoption of NGS based assays for many research and clinical labor ...

DESCRIPTION provided by applicant B cell lymphoma is cancer of B lymphocytes and accounts for more than deaths in the U S each year While many patients respond to currently available therapy there is a high rate of cancer relapse and inability for the patients o tolerate chemotherapy Thus there is a significant need to make available to these patients newer therapies that are more e ...

Significant energy is required to operate and maintain the extensive U.S. military mission around the world. This equates to significant costs to the country. Smart power microgrids have proven to significantly increase efficiency, as well as enable the u

DESCRIPTION provided by applicant CKD chronic kidney disease is a progressive disease which is reported to affect of the worldandapos s population End stage renal disease ESRD is the fifth and final stage of CKD ESRD will affect million people worldwide in and more than Americans at a cost of more than $ billion in the U S alone Elevated serum phosphorus Pi is th ...

DESCRIPTION provided by applicant Introduction The Blink based Communication BLINC System will allow any patient who retains oculomotor control to reliably signal for assistance and communicate basic requests to a caregiver It uses infrared IR cameras and illuminators to continuously monitor a patient in bed and to detect blink signals even in a dark room It is specifically designed so ...

DESCRIPTION provided by applicant The current standard of care for epidural blockades and related spinal anesthesia procedures is manual palpation of spinal bone landmarks followed by andquot blindandquot needle insertion However in the obese segment of the population estimated at approximately of the total US population spinal bone landmarks are covered with thick layers of fat and ar ...

DESCRIPTION provided by applicant Non small cell lung cancer NSCLC is the most common lung cancer Half of NSCLC shows WNT activation marking poor survival StemSynergy Therapeutics Inc SSTI has identified a family of WNT inhibitors based on a novel chemical scaffold with our lead molecule SST demonstrating efficacy against WNT driven colorectal cancer In Phase I SBIR studies many ...

DESCRIPTION provided by applicant Severe oxalate related conditions such as primary hyperoxaluria PH secondary hyperoxaluria SH as a result of short bowel syndrome chronic inflammatory bowel disease cystic fibrosis post bariatric and other malabsorption syndromes Zellweger spectrum disorders ZSD and chronic and end stage renal failure continues to be a healthcare problem without ...

DESCRIPTION provided by applicant Pressure ulcers are a major health problem affecting millions of adults in the USA They can be a significant site for infection leading to complication such as septicaemia and osteomyelitis in addition to causing significant pain and suffering compromised quality of life financial burden and morbidity mortality In conjunction with an aging population pa ...