Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Optimized lactoferrin for treatment of intracerebral hemorrhage

    SBC: PHARMAREVIEW CORPORATION            Topic: NINDS

    DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Integrated Bioinformatics Analysis Suite for targeted NGS of clinical specimens

    SBC: ASURAGEN, INC.            Topic: 400

    DESCRIPTION provided by applicant With the advent of rapid bench top sequencers such as the PGM and MiSeq the potential to transform cancer diagnosis and patient care is great Although sequencing instrumentation has become relatively affordable the need for NGS data analysis and interpretation still remains a big hurdle to the adoption of NGS based assays for many research and clinical labor ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. 2'-Fluorophosphophloretin (2FP)in the Treatment of Chronic Renal Failure

    SBC: DuoPhos            Topic: 400

    DESCRIPTION provided by applicant CKD chronic kidney disease is a progressive disease which is reported to affect of the worldandapos s population End stage renal disease ESRD is the fifth and final stage of CKD ESRD will affect million people worldwide in and more than Americans at a cost of more than $ billion in the U S alone Elevated serum phosphorus Pi is th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Militarized Power Line Communication

    SBC: 5-D SYSTEMS, INC.            Topic: OSD12EP7

    Significant energy is required to operate and maintain the extensive U.S. military mission around the world. This equates to significant costs to the country. Smart power microgrids have proven to significantly increase efficiency, as well as enable the u

    SBIR Phase II 2014 Department of DefenseOffice of the Secretary of Defense
  5. Development of a WNT Inhibitor for Advanced Stage Lung Cancer

    SBC: Stemsynergy Therapeutic            Topic: 102

    DESCRIPTION provided by applicant Non small cell lung cancer NSCLC is the most common lung cancer Half of NSCLC shows WNT activation marking poor survival StemSynergy Therapeutics Inc SSTI has identified a family of WNT inhibitors based on a novel chemical scaffold with our lead molecule SST demonstrating efficacy against WNT driven colorectal cancer In Phase I SBIR studies many ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Oxalate Reduction by Oral Administration of Oxalate Degrading Enzymes

    SBC: CAPTOZYME LLC            Topic: 400

    DESCRIPTION provided by applicant Severe oxalate related conditions such as primary hyperoxaluria PH secondary hyperoxaluria SH as a result of short bowel syndrome chronic inflammatory bowel disease cystic fibrosis post bariatric and other malabsorption syndromes Zellweger spectrum disorders ZSD and chronic and end stage renal failure continues to be a healthcare problem without ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Injectable microgel for soft tissue repair

    SBC: ROCHAL INDUSTRIES, LLP            Topic: 300

    DESCRIPTION provided by applicant Pressure ulcers are a major health problem affecting millions of adults in the USA They can be a significant site for infection leading to complication such as septicaemia and osteomyelitis in addition to causing significant pain and suffering compromised quality of life financial burden and morbidity mortality In conjunction with an aging population pa ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A novel broad-spectrum influenza vaccine

    SBC: KJ Biosciences LLC            Topic: NIAID

    DESCRIPTION provided by applicant Influenza viruses constantly undergo antigenic changes which pose great challenges for development of vaccines against influenza epidemics as well as pandemics There are at least known subtypes of influenza A viruses which fall into two broad phylogenetic groups Current trivalent inactivated vaccines TIV H H and B for seasonal influenza are not suit ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Kiddio: Food Fight- Training Vegetable Parenting Practices

    SBC: Archimage, Inc.            Topic: N

    DESCRIPTION provided by applicant Higher vegetable intake has been related to lower risks of diabetes cardiovascular disease several cancers and obesity adiposity later in life Yet children are eating vegetables well below recommended amounts Parents are important influencers on the dietary intake of young children but they commonly report difficulty getting their child to eat vegetables ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Engineering of Human Corneal Endothelial Grafts

    SBC: TISSUETECH, INC.            Topic: W

    DESCRIPTION provided by applicant The corneal endothelium plays a pivotal role in maintaining corneal transparency Unlike in other species the human corneal endothelium is notorious for its limited proliferative capacity in vivo after diseases injury aging and surgery Persistent corneal endothelial dysfunction leads to sight threatening bullous keratopathy Presently the only solution to ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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