Award Data

A DOT IMMUNOASSAY FOR THE DETECTION OF ACROSOME REACTION OF HUMAN SPERM WILL BE DEVELOPED FOR USE IN THE DETECTION OF MALE INFERTILITY. SCREENING TESTS FOR THE DETERMINATION OF THE CAUSES OF INFERTILITY AND SCREENING SEMEN SAMPLES FOR SPERM BANKING HAVE BECOME MAJOR RESPONSIBILITIES OF FERTILITY CLINICS. HOWEVER, NO SIMPLE METHOD CURRENTLY EXISTS FOR THE DETERMINATION OF THE FUNCTIONAL ABILITY OF ...

DESCRIPTION (provided by applicant): Bladder cancer is a common and costly disease. More than 60,000 new cases of bladder cancer are diagnosed each year in the U.S. It is the fourth most common cancer among men and the 10th among women, with a prevalence of about 500,000 in the US. Our compact NMR device will provide a rapid, accurate differential diagnosis of bladder cancer by detecting the tumor ...

DESCRIPTION (provided by applicant): This proposed project is motivated by the fact that comprehensive, broad-scale screening of diabetics for retinopathy is economically prohibitive without the introduction of computer-assisted diagnosis of retinal images. Over 20 million people in the U.S. have diabetes and it is estimated that less than half of thos ...

This prototype product line will result in a "health score card"/"clinical report card" forconsumers to be used to assist them with their decisions regarding health care choices. Consumersatisfaction, quality and clinical outcomes data from both the inpatient and outpatient settings, will beintegrated into a survey system supported by software, with databasing and report generatingcapabilities. Ou ...

DESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. P-selectin mediates the first step in the recruitment of white blood cells to sites of inflammation. Vasoocclusion is precipitated by a P- selectin-mediated adhesion of sickled red ...

DESCRIPTION (provided by applicant): The objective of this proposal is to examine the efficacy of CLT-005 in reducing ocular inflammation and that occurs during endophthalmitis. Endophthalmitis occurs following the introduction of foreign pathogens into the eye. In addition to pathogenic virulence, the infiltration of immune cells into the eye is a major factor is contributing to loss of vision. T ...

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MRC PROPOSES TO DEVELOP A SAFETY PERFORMANCE INDICATOR (PI) OF THE ELECTROMAGNETIC (EM) PROTECTION STATUS OF A NUCLEAR POWER PLANT (NPP). WE BELIEVE THAT SUCH A PI IS NEEDED BECAUSE: (1) EM ENVIRONMENTAL POLLUTION IS ON THE INCREASE,(2) ADDITIONAL EM THREATS MUST BE EVALUATED, AND (3) DISRUPTION OF NPP OPERATIONS BY EM EFFECTS CAN AND MUST BE AVOIDED. PREVIOUS STUDIES HAVE ADDRESSED THE ISSUE OF E ...

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DESCRIPTION (provided by applicant): Cancer research that translates into simple, easy to understand information is a challenge in mainstream USA. A lack of English language proficiency, trouble accessing health care, and socio-cultural barriers are challenges for monolingual Latinos. As of 2006, the estimated Hispanic/Latino population in the United States was 44 million (1). Almost 25 % of the L ...