Award Data

Adenosine produces coronary vasodilation through activation of A-2a adenosine receptors. However adalso acts at A1 adenosine receptors to slow atrioventricular conduction and when injected into man ican be blocked with A1 receptor antagonists. DTI has synthesized a number of adenosine analogs that2a subtype of adenosine receptor and have identified WRC-0470 as a potent selective short acting corou ...

Plasmid borne carbapenem resistance has become a serious global threat in hospital settings As hospitals face a dwindling number of treatment options there is a great urgency to track the movement of carbapenem resistant plasmids and the associated resistant genes While whole genome sequencing has great diagnostic potential plasmids pose a unique set of challenges as they lack a clear well de ...

A DOT IMMUNOASSAY FOR THE DETECTION OF ACROSOME REACTION OF HUMAN SPERM WILL BE DEVELOPED FOR USE IN THE DETECTION OF MALE INFERTILITY. SCREENING TESTS FOR THE DETERMINATION OF THE CAUSES OF INFERTILITY AND SCREENING SEMEN SAMPLES FOR SPERM BANKING HAVE BECOME MAJOR RESPONSIBILITIES OF FERTILITY CLINICS. HOWEVER, NO SIMPLE METHOD CURRENTLY EXISTS FOR THE DETERMINATION OF THE FUNCTIONAL ABILITY OF ...

THE LONG-TERM GOAL OF THIS WORK IS TO PRODUCE AN INEXPENSIVE, ACTIVELY CONTROLLED VEHICLE SEAT SUSPENSION SYSTEM TO CONTROL LOW BACK INJURIES CAUSED BY VERTICAL VIBRATION EXPOSURE. THE SPECIFIC AIM IS TO DESIGN A LOW POWERED SYSTEM CAPABLE OF NEW OR RETROFIT INSTALLATION. THIS PHASE I PROJECT WILL DEMONSTRATE THE FEASIBILITY OF USING ACTIVELY CONTROLLED SHOCK AND VIBRATION ABSORBERS. THIS WILL INV ...

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With the combined effects of a rapidly growing elderly population and advances in medicaltechnology, the need for decision making about appropriate medical treatments for elderly individualshas increased. Education about advance directives, legal documents which identify patients' decisionsregarding medical treatments, has not been systematically directed toward elderly adults residing in thecommu ...

This project is to design develop and test a culturally sensitive computer- interactive program forstyle, health, and dietary practices of African American women. The "Afro-SISTER" Program is the acrAfro-Sensitive Information System To Evaluate Risk" (SISTER) of nutrition-related diseases. The progprompted on a touch-sensitive computer screen. It will display culturally relevant activities, ethnil ...

This project will explore the translational potential of a new PET molecular imaging probe Ga PC for detecting very small cancers and distinguishing between localized and metastasized cancers in bone and soft tissue mouse models Ga PC will be evaluated for metastatic prostate PC and pancreatic PaCa cancers Early detection of the most lethal PaCa with andlt survival for y ...

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