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Recent cognitive research indicates that military teams operate effectively in high-stress, information-rich environments when they 1) share mental models of the battlefield situation and the team; 2) critique their situation model to develop clear goals for information retrieval; 3) effectively communicate information needs to others; and 4) anticipate and counteract information overload. We pro ...

Inappropriate trust of automation can lead to suboptimal performance, in which the respective capabilities of humans and computers are not effectively exploited. In some cases, over- or under-reliance can lead to catastrophe. The primary objectives of the proposed Phase I work are (1) to develop a systematic general framework for training users of decision aids, with particular attention to the ...

Decision Science Associates, Inc. (DSA) proposes to design and prototype an automated decision aid for the assessment of pre-flight risk by Army rotorcraft pilots. This aid will support the rapid assessment of risk based on readily available information. Phase I consists of 4 tasks. In Task 1 we will identify sources of information and determine the critical predictive factors and the types of dat ...

Information on the effect of long term dormant storage is essential for making correct parts selection and design decisions for next generation strategic programs of particular concern is the effect of exposure to elevated temperature and humidity, which may produce more corrosion in stored devices than in operating devices where power dissipation reduces moisture condensation. An accelerated age ...

This Small Business Innovative Research Phase I project has the primary objective of coating two sides of a substrate with High Temperature Superconductor (HTS) thin films and patterning them into microwave devices. Double sided HTS films offer reduced volume, less weight and higher performance than conventional components. The challenge in coating both sides of a substrate is protecting the opp ...

IGEN, Inc. proposes to construct a library of functional binding domains, encompassing a vast repertoire of binding specificities, for display on the surface of bacteriophage. The displayed domains can be selected against a variety of antigens to allow the rapid isolation of monospecific binding reagents for use in immunological based detection assays. This approach provides significant time and ...

Frog Embryo Teratogenesis Assay: Xenopus (FETAX) is a 96-h, whole-embryo bioassay designed to detect potential developmental toxicants. The primary goal of this research is to improve the predictability and increase the overall utility of FETAX as a screen for developmental toxicants that pose a hazard to human health. Since Xenopus laevis embryos lack mixed-fliriction oxidase metabolism (cytoch ...

Optimization of antibody affinity and specificity is of paramount importance to the military for the development of biological warfare agent receptors and vaccine components. Exhaustive saturation mutagenesis of the complete antigen binding site for such optimization must typically involve the construction and characterization of several hundred mutants. Using conventional mutagenesis, the expen ...