Award Data

THE NEED TO MAP AND SEQUENCE DNA IN THE HUMAN GENOME IS OF CRUCIAL IMPORTANCE FOR A BETTER UNDERSTANDING OF GENETICS AND DISEASE PROCESSES. CURRENT DNA SEQUENCING PROCEDURES ALMOST UNIVERSALLY REQUIRE GEL ELECTROPHORESIS OF DNA FRAGMENTS, AND SEVERAL LABORATORIES ARE DEVISING PROCEDURES TO AUTOMATE AS MANY STEPS OF THIS PROCESS AS POSSIBLE. SEQUENCING BY HYBRIDIZATION (SBH) PROPOSED BY DRMANAC ET ...

THE USE OF TRACERS TO TAG WELL GAS WHICH IS REINJECTED INTO OIL RESERVOIRS HAS ACHIEVED CONSIDERABLE SUCCESS IN CHARACTERIZING THE STRUCTURE AND GEOMETRY OF THE RESERVOIRS. IDEALLY, THE TRACER SHOULD BE DETECTABLE OVER A WIDE DYNAMIC RANGE, PARTICULARLY IN FIELDS WHERE LARGE VOLUMES OF GAS ARE INJECTED. THE OBJECTIVE OF THE PROPOSED RESEARCH IS TO DEMONSTRATE ORDERS-OF-MAGNITUDE INCREASE IN DYNAMI ...

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THIS PROJECT WILL RESULT IN THE DEVELOPMENT OF A NEW TECHNOLOGY FOR MEASURING THE QUANTITY AND LOCATION, WITH SUBMICRON RESOLUTION, OF BORON IN BIOLOGICAL CELLS IN SUPPORT OF THE BORON NEUTRON CAPTURE THERAPY (BNCT) PROGRAM. THIS PROJECT THUS ADDRESSES THE MAJOR UNSOLVED TECHNICAL ISSUE IMPACTING BNCT CLINICAL EFFICACY. BNCT IS APROMISING RADIATION THERAPY IN WHICH NEUTRONS ARE USED TO ACTIVATE BO ...

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