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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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SECONDARY PREVENTION OF ALCOHOLISM VIA COMPUTER SOFTWARE
SBC: Alcohol Self-control Program Topic: N/AN/A
SBIR Phase I 1990 Department of Health and Human Services -
Development of immunoassays for highly sensitive diagnostic monitoring of traumatic brain injury using novel astroglial injury-defined biomarkers
SBC: Immunarray USA, Inc. Topic: 101ABSTRACT Traumatic brain injuryTBIis an expanding public health epidemic with complex pathophysiology that is difficult to diagnose and thus treatTBI blood testing should provide simplereliablereal timeobjective diagnostic monitoring and outcome prediction across the entire severity spectrumNeurotrauma biomarkers with insight into underlying TBI processes can address these needsAt UCLADrWanner s t ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Smartphone phenotype collection for diagnostic screening of mild cognitive impairment
SBC: PARABON NANOLABS, INC. Topic: NIAProject Summary This project addresses a critical need for early detection of mild cognitive impairment (MCI) and other Alzheimer's-related dementias (ADRD). Advances in smartphone hardware, computer vision, and machine learning have enabled the possibility of producing smartphone-based cognitive testing applications able to collect electronic sensor data and transform it into highly informative ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel, Low-Cost Mobile Metabolic Measurement (M3) System
SBC: BARRON ASSOCIATES, INC. Topic: RSummary Abstract Indirect calorimetry is based on measurement of the exchange of respiratory gasesAll aerobic energy releasing reactions in the body use oxygenoxygen consumptionV Ois proportional to energy expenditureEEResearchgrade indirect calorimetry systems measure V Ocarbon dioxide productionV COand minute ventilationV Ebreath by breath and then average results over multiple breaths to obtain ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Targeting galectin-3 to overcome drug resistance in metastatic prostate cancer therapy
SBC: GLYCOMANTRA INC Topic: 102Project Summanry Abstract Although abirateroneZytigaand enzalutamideXtandirepresent significant advances in the treatment of metastatic castration resistant prostate cancermCRPCall eventually acquire drug resistance over time and become lethalThereforenew research strategy and intervention are urgently needed to develop effective therapy for CRPCWe have shown that galectinGala beta galactoside bin ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
To develop a nanoSPRi sparing assay.
SBC: LUNA INNOVATIONS INCORPORATED Topic: NIAIDProposes to develop a novelstandardized immune assay that improves monitoring of several biomarkerscytokinesassociated with immunologic pathways of AD with the constraint of having a limited amount of biological samplesThis overall goal is supported by the following program objectivesPhase IDemonstrate proof of concept of nanoSPRiSAas a sensitive and efficient technique in assessing cytokines in h ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
The objective of this contract is to develop a novel LBL RNA vaccine that can be administered to induce long-lasting protection against HIV challenge.
SBC: LUNA INNOVATIONS INCORPORATED Topic: NIAIDExtensive efforts have gone towards safe and effective vaccines for Human Immunodeficiency VirusHIVprevention and treatmentAlthough many strategies have been attempted for HIV vaccine developmentnone have been successfully establishedOne category of vaccines gaining increased popularity is RNA based vaccineswhich are vaccines containing antigens encoded by RNA and can be delivered by viral or usin ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
BT-11: A First-in-class Oral Therapeutic for Inflammatory Bowel Disease
SBC: Biotherapeutics, Inc. Topic: NIAIDBTA First in class Oral Therapeutic for Inflammatory Bowel Disease Biotherapeutics IncBTIdevelops oral first in class therapeutics for autoimmune diseasesBTa lead compound for treating inflammatory bowel diseaseIBDbelongs to a new chemotype and targets the novel Lanthionine Synthetase C LikeLANCLpathwayBTI will file an IND for BTinmonthsSignificanceIBD afflicts overmillion Americans andmillion peo ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
DICER-Dx: The First Liquid Biopsy for Early Detection and Monitoring of DICER1 Syndrome Pediatric Cancers
SBC: RESOURCEPATH LLC Topic: 102PROJECT SUMMARY ABSTRACT Pleuropulmonary blastomaPPBis the most common lung cancer of childhoodand usually the earliest indication of DICERsyndromea genetic predisposition to early onset embryonal tumors of multiple organ sitesThe syndrome is defined by germline mutations in the DICERgeneOMIMIn addition to PPBthe spectrum of syndromic neoplasias includes ovarian Sertoli Leydig cell tumorcystic nep ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Novel Immunotherapy Targeting Cancer Stem Cells for the Treatment of Triple-Negative Breast Cancer
SBC: Agilvax, Inc. Topic: 102Agilvax s AXis an Immunotherapy for Triple Negative Breast CancerAgilvax is developing cancer immunotherapies and vaccines with its proprietary virus like particleVLPplatform technologyAgilvax s lead productAXis an immunotherapy for triple negative breast cancerTNBCtargeting cancer stem cellsCSCthat is designed for use in combination with existing and emerging therapiesTNBC is extremely aggressive ...
SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health