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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. NEURON2GPU: Transformative Neural Simulation Using Desktop GPU Technology

    SBC: INFORMED SIMPLIFICATIONS, LLC            Topic: NIMH

    DESCRIPTION (provided by applicant): Researchers are now able to perform computational physiology and pharmacology experiments on realistic model neurons with accurate geometries and full complements of membrane biophysics and biochemistry; however, the practical utility of such simulations are restricted because of the limitations of current commodity computer hardware. We will provide real time, ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  2. PREDICTABLE REAL-TIME MULTIPROCESSING IN AIRBORNE SYSTEMS

    SBC: Unisoft Consulting Inc            Topic: N/A

    N/A

    SBIR Phase I 1996 National Aeronautics and Space Administration
  3. Alum-absorbed subunit vaccine to prevent intestinal amebiasis

    SBC: TECHLAB, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): We propose to produce a subunit vaccine for Entamoeba histolytica and test it in mice for immunogenicity and for protection from intestinal amebiasis. Entamoeba histolytica is a Category B NIH Biodefense pathogen due to its low infectious dose and food and water-bone transmission, and an important cause of diarrhea in children in Africa, Asia and Latin America ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  4. Rapid, disposable, nucleic acid diagnostic device for multiplexed point of care f

    SBC: MESA TECH INTERNATIONAL, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Rapid and accurate identification of highly infectious and pathogenic disease is extremely important for the early forecast of outbreak risk and the effective deployment of medical and administrative countermeasures. Unfortunately, current diagnostics for use at the point-of-care (POC) are largely immunological assays that often lack adequate sensitivity, speci ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  5. SECONDARY PREVENTION OF ALCOHOLISM VIA COMPUTER SOFTWARE

    SBC: Alcohol Self-control Program            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  6. Ultra-Compact MRI: A new cost-effective tool optimized for developmental biology

    SBC: ABQMR, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): Research using Xenopus (frog) embryos, a model system of major importance in many areas of biomedicine, is hampered in a fundamental way by their opacity. No device for non-destructively imaging the interiors of these specimens is generally available. The long-term goal at ABQMR, Inc. is to utilize unique capabilities in the field of miniaturized NMR and MRI in ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Developing a plectin-1 targeted imaging agent for the detection of pancreatic can

    SBC: iTi Health            Topic: NCI

    DESCRIPTION (provided by applicant): Pancreatic ductal adenocarcinoma (PDAC) is an intractable clinical problem, typically presenting with metastasis at the time of diagnosis and exhibiting profound resistance to existing therapies. Currently, the standarddiagnostic course includes CT or MRI scans which do not have optimal sensitivity and specificity for accurately diagnosing and determining resec ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  8. Novel emulsion-based formulation of the anti-glaucoma MSH-1001 for improved topic

    SBC: Charlesson, LLC            Topic: NEI

    DESCRIPTION (provided by applicant): This Small Business Innovation project aims to develop an innovative eye drop formulation for the treatment of glaucoma and ocular hypertension. Charlesson has acquired from Danube Pharmaceuticals MSH-1001, a new smallmolecule compound (previously known as DNB-001 or KR- 31378). MSH-1001 is has both ocular hypotensive and neuroprotectant properties. It is an AT ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  9. Multitargeted Therapy for Age-related Macular Degeneration

    SBC: Charlesson, LLC            Topic: NEI

    DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is a sight-threatening disease which represents the leading cause of blindness and visual impairment in elderly individuals in developed countries. Recently, laser and photodynamic therapies with limited clinical benefit have been partially replaced by anti-vascular endothelial growth factor (VEGF) therapies. Clinical ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
  10. TAS::75 0849::TAS SBIR TOPIC 307 PHASE I NOVEL IMAGING AGENTS TO EXPAND THE CLINICAL TOOLKIT FOR CANCER DIAGNOSIS, STAGING, AND TREATMENT

    SBC: iTi Health            Topic: NCI

    Phase I - Topic 307 The long term objective of this work is to transform the clinical practice of diagnosing and treating pancreatic cancer through the development of a targeted imaging reagent. The 5-year survival rate for patients diagnosed with pancreatic cancer is less than 5%. Those with respectable disease have a much greater likelihood of survival, however 80% of patients are diagnosed wit ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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