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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of an Anti-PSGL-1 Antibody to Treat Crohn's Disease

    SBC: SELEXYS PHARMACEUTICALS CORPORATION            Topic: NIDDK

    DESCRIPTION (provided by applicant): The primary objective of this proposal is to develop and commercialize a safe and more effective therapy for the treatment of Crohn's Disease, an inflammatory bowel disease. Crohn's Disease is a chronic inflammatory disorder of the gastrointestinal tract that affects some 500,000 patients in the US. Selexys Pharmaceuticals is developing a fully human anti-PSGL- ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Multiplex Diagnostic for Enteric Category B Pathogens and Intestinal Biomarkers

    SBC: TECHLAB, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Our goal is development of a multiplex immunodiagnostic panel specific for Giardia, Cryptosporidium, E. histolytica, and shiga toxin-producing Shigella and E. coli detection in stool. Additional effort will quantify the fecal biomarkers lactoferrin and hemoglobin, indicators of intestinal inflammation and hemorrhage. The full multiplex panel will provide rapid ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  3. PREDICTABLE REAL-TIME MULTIPROCESSING IN AIRBORNE SYSTEMS

    SBC: Unisoft Consulting Inc            Topic: N/A

    N/A

    SBIR Phase I 1996 National Aeronautics and Space Administration
  4. Novel anti-viral agents to treat influenza

    SBC: ALEXANDER BIODISCOVERIES, LLC            Topic: NIAID

    DESCRIPTION (provided by applicant): Yearly influenza epidemics affect about 5 - 15% of the world's population and estimates of annual mortality range from 250,000 - 500,000, including approximately 30,000 deaths and 200,000 hospitalizations in the United States. In addition, the likelihood of a severe influenza pandemic caused by a newly emergent strain of the virus is very high, given that three ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  5. Synergistic vaccine adjuvants that stimulate both innate and adaptive immunities

    SBC: Bio-Synthesis, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): The objective is to develop a glycoside adjuvant or immune agonist carrying the chemical structures needed to concurrently stimulate in a cooperative manner both innate and adaptive immunities, leading to a synergistic effect on the cellular (Th1) and humoral (Th2) immunities. It is likely that these adjuvants would also stimulate strong mucosal immunity. Studi ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  6. SECONDARY PREVENTION OF ALCOHOLISM VIA COMPUTER SOFTWARE

    SBC: Alcohol Self-control Program            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  7. A Novel CNS-Penetrable Antiretroviral

    SBC: Jericho Sciences, LLC            Topic: NIMH

    DESCRIPTION (provided by applicant): Since the introduction of highly active antiretroviral therapy (HAART) in the mid-1990's for treatment of human immunodeficiency virus type 1 (HIV-1) infection, overall incidence rates of associated neurological maladies have declined. Unfortunately, the HIV-associated prevalence of both central nervous system (CNS) and peripheral nervous system (PNS) disorder ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Next Generation Capsule Endoscopy Video Data Acquisition and Visualization Platfo

    SBC: Altrum Technologies, Inc            Topic: NCRR

    DESCRIPTION (provided by applicant): Gastrointestinal (GI) malignancies are the most common cause of cancer in the world. Of the 10.8 million people in the world each year who develop cancer, approximately 3.3 million have GI malignancies. Aside from prevention, effective, low cost, and comfortable early diagnosis technologies are urgently needed to improve this situation. Traditional endoscopic o ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. Stimuli Responsive Topical Gels for Mechanically Assisted Wound Debridement

    SBC: LYNNTECH INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Debridement of dead, damaged and/or infected tissue from thermal burn wounds and a certain subset of ischemic and necrotic diabetic foot wounds is a commonly utilized wound preparation modality before the application of fillers, dressings or grafts. The existing wound debridement techniques have serious issues such as invasiveness and impreciseness, painful ...

    STTR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a diagnostic instrument to manage hemostasis in chronic liver dise

    SBC: HEMOSONICS            Topic: NIDDK

    DESCRIPTION (provided by applicant): The clinical evaluation and management of hemostasis in the 5 million patients affected by chronic liver diseases (CLD) is poorly understood. Data presented at two International Symposia on Coagulation in Liver Disease and summarized in a recent edition of Clinics in Liver Disease strongly support the presence of an unmet clinical need for investigation in this ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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