Award Data

Adenosine produces coronary vasodilation through activation of A-2a adenosine receptors. However adalso acts at A1 adenosine receptors to slow atrioventricular conduction and when injected into man ican be blocked with A1 receptor antagonists. DTI has synthesized a number of adenosine analogs that2a subtype of adenosine receptor and have identified WRC-0470 as a potent selective short acting corou ...

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THIS PROJECT WILL DEVELOP THE APPLICATION OF STATE-OF-THE-ART CHARGE-COUPLED DEVICE (CCD) IMAGE DETECTORSTO THE PROBLEM OF THE AUTOMATIC ANALYSIS OF DNA-SEQUENCING GELS. SUCCESS OF THIS PROJECT WILL RESULT IN COMMERCIALIZATION OF AN INSTRUMENT CAPABLE OF READING, INTERPRETING, AND STORING DNA SEQUENCE INFORMATION DIRECTLY FROM AN AUTORADIOGRAM OF A DNA-SEQUENCING GEL. SUCH AN INSTRUMENT WILL STREN ...

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CURRENTLY AVAILABLE EVOKED-POTENTIAL MACHINES GENERALLY RELYON ENSEMBLE AVERAGING TO SEPARATE THE EVOKED-POTENTIAL WAVEFORMS FROM ACCOMPANYING NOISE. THIS TECHNOLOGY IMPOSES LIMITS ON THE UTILITY OF THESE SYSTEMS IN "HIGH-NOISE" ENVIRONMENTS AND WHEN RAPID RESOLUTION OF POTENTIALLY CHANGEABLE EVOKED POTENTIALS IS CLINICALLY ESSENTIAL, SUCH AS IN THE OPERATING ROOM OR THE INTENSIVE CARE UNIT. CORTE ...

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PERSONALIZED DECISION ANALYSIS (PDA), BASED ON THE MAXIMIZATION OF SUBJECTIVE EXPECTED UTILITY, IS ACADEMICALLY WELL ESTABLISHED AS A NORMATIVE MODEL OF DECISION MAKING. PRACTITIONERS WORKING ON REAL DECISIONS HAVE RECENTLY DEVELOPED VARIANTS THAT HAVE PROVEN TO BE USEFUL PRESCRIPTIVE TOOLS FOR PROFESSIONAL DECISION MAKERS. BASED ON COGNITIVE AND EDUCATIONAL PSYCHOLOGY RESEARCH, IT IS HYPOTHESIZED ...

This project is to design develop and test a culturally sensitive computer- interactive program forstyle, health, and dietary practices of African American women. The "Afro-SISTER" Program is the acrAfro-Sensitive Information System To Evaluate Risk" (SISTER) of nutrition-related diseases. The progprompted on a touch-sensitive computer screen. It will display culturally relevant activities, ethnil ...

WE PROPOSE TO DEVELOP A PORTABLE MONITORING SYSTEM CAPABLE OF DETECTING TRACE QUANTITIES OF RADIONUCLIDES IN SOILS USING A HIGH RESOLUTION CADMIUM TELLURIDE ARRAY DETECTOR AND A RUGGED MULTICHANNEL DATA LOGGER. THE PROPOSED MONITORING SYSTEM BUILDS UPON THE DESIGN OF A SIMPLE MONITOR DEVELOPED TO AID IN THE DECONTAMINATION AND DECOMMISSIONING OF A URANIUM PLANT. THE SIMPLE SYSTEM IMPROVED THE SPEE ...

We will build a prototype personal computer-based system called AERES, Alcohol Effects Research Emusystem. Emulations are real-time interactive immersive experiences. Emulations receive inputs from oacting on real physical devices, and bio-sensors while outputing to the subjects synthesized graphicEmulations can be created to measure subjects' responses and to verify hypothesized behavioral modelu ...