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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. NOVEL ADENOSINE A2A AGONISTS IN RENAL TISSUE PROTECTION

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The development of new treatments for the effective reduction of renal injury associated with acute renal failure and kidney transplantation will have a great impact on health care delivery to patients with renal disease. Acute ischemic renal failure affects 5 percent of hospitalized patients and has a mortality rate approaching 50 percent. At present, dialysis ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  2. A2A ADENOSINE AGONISTS AS NEUROPROTECTANTS

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The central goal of this research is to develop a new drug to prevent spinal cord reperfusion injury secondary to aortic clamping that occurs frequently during thoracic surgery. Irreversible spinal cord injury resulting in paraplegia or paraparesis is the single most devastating complication of surgery on the thoracic and thor ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  3. ADVANCED DIABETES MANAGEMENT SYSTEM

    SBC: Adherence Technologies Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): For the 10 million people in the U.S. with Type 2 diabetes, it is essential to follow strict regimens that include diet, weight, exercise, eye care and foot care. The prescribed regimen promotes glycemic control, which is correlated with better health. Many have proposed interventions that are either time/labor intensive and costly (regular phone calls from nu ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  4. ACCUNURSE SYSTEM

    SBC: Adherence Technologies Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): The AccuNurse System has been successfully developed in Phase I to provide an easy-to-use "mentor" and communications tool for CNAs and nurses in skilled nursing units. Wireless and advanced speech technologies are merged into a conversational system that provides: individualized resident information, paperless documentation at the point of care, and many other ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  5. SMALL MOLECULE BLOCKERS OF B. ANTHRACIS TOXIN

    SBC: Innovative Biologics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this SBIR proposal is the identification of small molecules capable of blocking the cytotoxic action of Bacillus anthracis lethal toxin by blocking the transmembrane pore formed by the protective antigen component of the toxin. Such molecules are envisioned for use as drugs for the treatment of anthrax. The strategy to identify such compoun ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  6. MULTIRESOLUTION AUTOFOCUSING FOR AUTOMATED CYTOGENETICS

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    The goal of this project is to develop innovative digital microscope autofocusing techniques for automated cytogenetics applications. We propose a novel multi-resolution image analysis approach to focus measurement and detection, based on the recently developed mathematical theory of wavelet transform. In comparison to currently available single-resolution techniques, the proposed method overcom ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  7. IMPROVED IMAGING FOR PRECISE CRYTPIC ANOMALY DETECTION

    SBC: Advanced Digital Imaging Research, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This project will further develop automated instrumentation and image analysis techniques to detect cryptic chromosomal rearrangements, which are difficult to detect by conventional cytogenetics. It combines two innovative FISH probes: "SubTelomeric" (STFISH) and "Multiplex" (MFISH), with sophisticated image analysis, ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  8. CO-AMPLIFIED RNAS FOR COMPARITIVE MICROARRAY ANALYSIS

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    Ambion, Inc. proposes to develop methods and reagents that will make it possible to compare the expression profiles of small RNA samples (

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  9. SIRNA DESIGN, PRODUCTION AND DELIVERY

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): RNA interference is a new and powerful research tool that can be used to down regulate or knock out a specific gene or genes in a variety of cell types and organisms. Currently this technology is being used to study gene function, but may one day be used for human therapeutics. The RNAi phenomenon was only recently demonstrated to be present in mammalian cells ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
  10. MULTI-SAMPLE COMPARATIVE RT-PCR

    SBC: AMBION DIAGNOSTICS, INC.            Topic: N/A

    Ambion, Inc. proposes to adapt its Comparative RT-PCR procedure to accommodate the comparative analysis of single transcripts across one hundred RNA samples. The proposed procedure involves reverse transcribing a collection of RNA samples using primers with identical anchored oligodT and PCR primer binding sites but intervening hybridization domains that are unique to each sample. Equal amounts o ...

    SBIR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health
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