Award Data

Recent advances in mammalian artificial chromosome design and engineering offer an alternative to existing methodologies for cellular bioengineering and address unmet needs to bioengineer more complex functionalities into human cells for subsequent commer

The objective of this proposal is to develop novel lead salt semiconductor quantum dot (QD) mid-infrared detectors for sensing and imaging applications. The proposed development is based on our recent study of PbSe photoconductive (PC) detector with a rec

This proposal aims to show the feasibility of designing a high-level data-parallel language extension to Python on graphics processing units (GPUs). This language extension cooperates with the CPython implementation and uses Python syntax for describing

Barron Associates proposes to develop probabilistic extensions for the model-based programming environment Simulink, developed by The MathWorks, Inc. These extensions will allow developers to model random variables, vectors, and matrices, as well as both discrete and continuous random processes as first-class objects within the Simulink language. Barron Associates will also develop extensions that ...

The social cognitive effects of the neuropeptide oxytocin have potential implications in matters related to national security. There are currently more than two hundred human trials studying the functions of oxytocin in clinical cohorts. However, problems associated with specificity and sensitivity of currently available oxytocin assay methods has been an impediment to advancement of research in t ...

The emergence of low cost GPS enabled sensors and mobile devices has dramatically increased the volume of streaming spatial data available. We propose to build streaming tools capable of doing the following in real time: (1) automatically extracting spatial coordinates from streams of (a) structured values like latitude and longitude coordinates, and (b) extracting and geocoding location indicato ...

The proposal described herein presents a novel Mode-Division-Multiplexing (MDM) to realize waveguide arrays with subwavelength waveguide pitches. Waveguide arrays are usually designed with waveguide pitches of about a few wavelengths in order to avoid cross-talk. Multiple-Input-Multiple-Output (MIMO) enabled MDM has been used to enhance data rate in multimode fibers beyond their dispersion limit. ...

Operational Technologies Corporation proposes to develop non-immunogenic DNA aptamers against unfractionated snake, scorpion, spider, and insect venoms as well as snake phospholipase A2 (PLA2) and melittin (major components of venoms) in Phase 1. OpTech will then test each of the final round aptamers for the ability to inhibit PLA2 and prevent cell lysis due to various venoms in a human fibroblast ...

AM Biotech proposes to develop X-Aptamer-functionalized NanoSponges (XANS) as a multi-valent snakebite antidote using synthetic, ambient-stable affinity molecules (X-Aptamers) coupled to nanoporous silica microparticles (nanosponges). XANS would be ambient-stable, universal, available in remote locations, and would not cause anaphylactic reactions. The antidote would be injected in the field at t ...

Logos Technologies proposes to modify its series hybrid-electric powertrain used in its acoustically-suppressed, powered parafoil, the DARPA ParaHawk, and integrate it into the existing off-road, electric motorcycle by BRD. By modifying and combining systems, Logos will significantly reduce risk and development time, demonstrating the hybrid powertrain in Phase I and then quickly integrating it i ...