Award Data

DESCRIPTION provided by applicant Heart failure and congenital heart defects threaten the lives of several thousand children each year The only FDA approved long term pediatric heart support device is the Berlin Heart Excor which is based on year old technology and is fraught with complications including blood clots forming in the device requiring frequent device replacement The recipien ...

Military and intelligence operations are gathering imagery from a variety of sources including ground-based sensors, aerial platforms, and satellites at rates far exceeding our ability to analyze or even transmit and archive this data. This imagery comprises not only still images but increasingly full-motion video (FMV); high-definition (HD), wide-area imagery (WAMI), and other high-resolution for ...

WORLD-WIDE WIND VELOCITY, BOTH SPEED AND DIRECTION, FROM THE GROUND THROUGH 50,000 FT. ALTITUDE CAN BE ACCURATELY MEASURED USING A SMALL SPACE-BASED PAYLOAD. THE PROPOW=SED PROJECT WILL DEMONSTRATE THAT RECENT DEVELOPED LASER, DETECTOR AND SPACECRAFT TECHNOLOGIES CAN BE EXPLOITED AND INTEGRATED INTO A SMALL, LOW COST, SPACE-BASED WIND MAPPING SYSTEM WHICH CAN BE CONFIGURED EITHER AS A MODULE AVOAR ...

ABSTRACT:This effort will provide both a rapid, satellite thermal modeling tool and deployable radiator system specific to Responsive Space needs. The thermal analysis tool will allow users to make rapid decisions and apply appropriate hardware from a specific RS thermal toolbox. The deployable radiators, being a key component of this toolbox, will provide near isothermal radiator surfaces and a h ...

DESCRIPTION provided by applicant Pulmokine is developing a novel inhaled PDGF receptor PDGFR kinase inhibitor PK as a treatment for Pulmonary Arterial Hypertension PAH The purpose of this Phase IIB Small Market Bridge Award is to progress PK through a phase A clinical trial for safety PAH is an orphan disease with high morbidity and mortality despite currently available treat ...

ABSTRACT: Space Situational Awareness is concerned with the physical characteristics, capabilities, operations, health, and potential threats posed by space objects. This information is gathered largely via radar and optical data collection facilities. Due to the increasingly large number of space objects and relatively limited number of collection facilities, it's important that collection operat ...

The Submarine Reliability Management System (SRMS) is a tool integrated into the TI14/APB13 increment of the AN/BYG-1 submarine combat system. SRMS monitors the host system for faults and degradations using datamining techniques, based on signatures defined in an extensible, Navy-managed set of XML-based Issue Definition File (IDF). This Phase II.5 effort will mature and extend SRMS to improve the ...

DESCRIPTION provided by applicant The global HIV AIDS epidemic continues to be fueled by the large number of individuals who do not know that they are infected The CDC is supporting programs to decrease this number by encouraging more frequent testing of all age groups as well as increasing the venues for testing including the recent FDA approval of an oral HIV Screening test for anti HIV anti ...

ABSTRACT:MZA partnered with the University of Notre Dame proposes advancement of aero-optical isolation hardware, data processing, and optical modeling for upgrade of AEDCs 16T wind tunnel. We will conduct testing at AEDC during Year 1 with mechanical diagnostics and an upgraded optical sensor with small-aperture access to the test section from outside the 16T pressure vessel. We will also design ...

Abstract The goal of this fast track SBIR proposal is to file an investigational new drugINDapplication for testing a novel anticancer drugFLthat is designed to overcome inherent and acquired treatment resistanceMany types of cancers are not detected until they are very advanced and have already become resistant to FDA approved treatmentsIn additionmany non advanced cancers respond well to initial ...