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DESCRIPTION (provided by applicant): Many cases of sensorineural hearing loss (SNHL) likely are caused by interruption of cochlear blood flow (CBF). Disruption of the internal auditory artery during surgical procedures to remove acoustic neuromas (ANs) probab'y account for many cases of postoperative deafness. Also, many cases of clinical SNHL, such as sudden SNHL, are thought to involve reductio ...

DESCRIPTION (provided by applicant): Absence of Oxalobacter formigenes (Oxf) from the GI-tract is a risk factor for development of hyperoxaluria and calcium oxalate kidney stones. Recent data now indicate that patients with recurrent urolithiasis have a lower prevalence rate of Oxf in their stools than non-stone forming individuals. In addition, urinary oxalate levels are higher in non-colonized i ...

DESCRIPTION (provided by applicant): Sjogren's syndrome is a human autoimmune disease of the salivary and lacrimal glands that results in a debilitating xerostomia (dry mouth) and xerophthalmia (dry eyes). This syndrome may present as either a primary autoimmune disease or as a secondary autoimmune disease most often concomitant with other connective tissue diseases or diabetes. Although classi ...

DESCRIPTION (provided by applicant): In Phase I Kestrel Corporation developed and demonstrated a retinal imaging system that combines multispectral imaging techniques with adaptive optics and image deconvolution to provide high resolution less than (

"Reflex triode bremsstrahlung sources potentially provide warm X-ray sources (20 keV to 500 keV), capable of generating high doses (~10 cal/g gold) over exposure areas of ~20 cm2. This needed capability allows experimental verification of warm X-ray inducedthermomechanical response, SGEMP, and box IEMP models for achieving component and system certification to hostile environments.In a reflex trio ...

DEVELOPMENT OF A HIGH FIDELITY, HIGH ENERGY DENSITY WATER SHOCK SIMULATOR APPEARS FEASIBLE. MISSION RESEARCH CORPORATION (MRC), WITH THE ASSISTANCE OF THE NEW MEXICO ENGINEERING RESEARCH INSTITUTE (NMERI), PROPOSES TO DEVELOP AN ELECTRICAL WATER SHOCK SIMULATOR WHERE AN ELECTRICAL DISCHARGE ACROSS A WELL DEFINED ELECTRODE GAP WILL PRODUCE A HOT PLASMA EXPANSION WHICH RESULTS IN A FAST RISE PRESSUR ...

Mission Research Corporation proposes the development of a unique FPGA (field programmable gate array) for applications in space and other military and civilian environments requiring the versatility of reconfigurability with retention of the configuration in an unpowered state. The FPGA will be capable of being configured once and retaining that configuration for a minimum of 10 years even with ...

The objective of this research is to develop a very low cost, in vitro, arterial blood gas (ABG) sensor and associated handheld readout system. ABG measurements are the most frequently ordered tests in intensive care units. The results of Phase I demonstrated excellent accuracy and reproducibility of the optical-based measurements. In addition, optical methods were developed to perform calibration ...

CURRENT ATTEMPTS TO USE THE PLASMA OPENING SWITCH (POS) FOR DECADE HAVE NOT YET BEEN ENTIRELY SUCCESSFUL DUE TO THE APPARENT INABILITY OF THE SWITCH TO OPEN EFFICIENTLY TO A HIGH-IMPEDENCE LOAD. RESEARCH DIRECTED TOWARD IMPROVING THE PERFORMANCE OF THE POS IN THE LONG-CONDUCTION TIME REGIME HAS BEEN FRUSTRATED BY THE INABILITY OF COMPUTATIONAL TOOLS TO OPERATE IN THE PARAMETER REGIMES OF INTEREST ...