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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel Antibacterial Agents That Target DNA Replication in Mycobacterium tuberculo

    SBC: Achillion Pharmaceuticals, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Mycobacterium tuberculosis (MTB) is probably the most ubiquitous microbial pathogen in the world today infecting one-third of the total population and causing millions of active tuberculosis (TB) cases each year. The economic costs are substantial and more than one million people die of TB infections each year. Before the arrival of antimicrobial therapy, TB wa ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  2. Thermal Protective Coatings for Interceptor Missiles

    SBC: Adherent Technologies, Inc.            Topic: MDA09007

    This SBIR project will address the combined effects of aerothermal heating, rain erosion, and moisture and gas diffusion on the degradation of interceptor missile radomes designed for hypersonic travel. A novel method of protecting hypersonic interceptor missiles from the rigors experienced at velocities several times the speed of sound is proposed. The technology is based on the conversion of a ...

    SBIR Phase I 2010 Department of DefenseMissile Defense Agency
  3. Dust Mitigation for the Lunar Surface

    SBC: Adherent Technologies, Inc.            Topic: X502

    The lunar surface is, to a large extent, covered with a dust layer several meters thick. Known as lunar regolith, it has been produced by meteorite impacts since the formation of a solid lunar surface billions of years ago. The regolith, while promising as a future building material for lunar installations, also poses a hazard in the form of dust clouds being generated by all forms of gas expans ...

    SBIR Phase II 2010 National Aeronautics and Space Administration
  4. Catalytic Suppressor System for Reducing Diesel Emissions

    SBC: Adherent Technologies, Inc.            Topic: BC

    This SBIR project will develop a new technology for the removal and destruction of NOx pollutants from diesel engine exhaust. Four important issues will be addressed in the project. The first issue will be applying a zeolite coating to reticulated catalyst supports with the correct chemical composition and pore size distribution. The second issue will be doping the zeolite metal with an ion exc ...

    SBIR Phase I 2010 National Science Foundation
  5. Shipboard Waste Volume Reduction and Treatment

    SBC: Adherent Technologies, Inc.            Topic: N092153

    The US Navy is seeking ways to treat typical ship-generated waste to minimize storage space required for waste storage during long-term deployments, with a special emphasis on the large items produced during cargo and ordinance handling. The best way to do this is to treat the waste as a resource, reducing its volume and producing useful energy or fuel from the waste decomposition process. Rather ...

    SBIR Phase I 2010 Department of DefenseNavy
  6. A Compact, Efficient Pyrolysis/Oxidation System for Solid Waste Resource Recovery in Space

    SBC: ADVANCED FUEL RESEARCH, INC.            Topic: X203

    Pyrolysis processing can be used in near term missions for volume reduction, water recovery (drying), stabilization, and enhanced water and oxygen recovery through thermochemical reactions. For longer term missions, the added benefits include production of fuel, multi-purpose carbon, and reactants for in-situ resource utilization (ISRU). The objective of the Phase I SBIR program was to demonstrate ...

    SBIR Phase II 2010 National Aeronautics and Space Administration
  7. Turbine Inlet Gas Temperature Measurement System

    SBC: ADVANCED FUEL RESEARCH, INC.            Topic: AF083260

    The Air Force is seeking new technology that will provide the means to accurately measure and monitor turbine inlet gas temperature in gas turbine engines, particularly in advanced engines operating at very high temperatures (>3,100 degree F). In Phase I of this program, Advanced Fuel Research, Inc. demonstrated that turbine inlet gas temperature can be determined from non-intrusive measurements ...

    SBIR Phase II 2010 Department of DefenseAir Force
  8. Development of a method to multiplex ChIP-SEQ and ChIP-chip experiments

    SBC: AFFOMIX, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The immediate objective of our research is to generate a method that will enable researchers to multiplex Chromatin ImmunoPreciptation-Sequencing (ChIP-Seq) analysis in a single Next generation DNA sequencing run. In the to-be-developed method: i) a set of antibodies directed against specific DNA-binding proteins are uniquely bar-coded with a DNA 'ZipCode;' ii) ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  9. High-throughput screening and identification of scFv antibodies against glycosyla

    SBC: AFFOMIX, INC.            Topic: NCRR

    DESCRIPTION (provided by applicant): The specific goal of this proposal is to develop a high-throughput method to identify scFv antibodies that recognize post-translationally modified proteins. We propose to complete a proof-of-concept for a new type of affinity screening process based on emulsion, secretion, and capture, which we term ESCape . In the proposed phage ESCape method, E. coli transfo ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  10. A bifunctional antibody screening system for both phage display and yeast two-hyb

    SBC: AFFOMIX, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): This is a proposal to establish a proof-of-principle for a vector system to isolate high-affinty antibodies through selective rounds in both yeast and Escherichia coli. Antibodies have quickly become extremely useful as therapeutic medicines to treat a wide-variety of disorders. We propose to develop a means of making the discovery of immunotherapeutics faster ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
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