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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of an Ad5 [E1-, E2b-] HIV-1 vaccine for use in Ad5 Immunized Vaccinee
SBC: Etubics Corporation Topic: N/ADESCRIPTION (provided by applicant): Current generation Adenovirus (Ad) vector vaccines deleted at the E1 or the E1, E3 regions have resulted in experimental potential to immunize against a variety of infectious diseases such as HIV. These Ad vectors permit the delivery of genes, which express proteins that stimulate the immune system. An advanced generation of Ad vectors with unique deletions of ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Development of an Anti-P-selectin Antibody for the Treatment of Sickle Cell Disea
SBC: SELEXYS PHARMACEUTICALS CORPORATION Topic: N/ADESCRIPTION (provided by applicant): Selexys Pharmaceuticals is developing a humanized monoclonal antibody drug directed against P-selectin for the treatment of vasoocclusive crisis in patients with sickle cell disease. P-selectin mediates the first step in the recruitment of white blood cells to sites of inflammation. Vasoocclusion is precipitated by a P- selectin-mediated adhesion of sickled red ...
SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Economic Spectroscopic Evaluation of Cervical Cancer
SBC: GUIDED THERAPEUTICS Topic: N/ADESCRIPTION (provided by applicant): Guided Therapeutics has developed the LightTouch(R), a non invasive, point of care device that uses a combination of fluorescence and reflectance spectroscopy to measure the entire ecto-cervix in an imaging format. Our test is intended for use prior to colposcopy by a trained healthcare professional (e.g., physician, nurse practitioner, physician's assistant) t ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Development of a Novel CEA Expressing Ad5 [E1-, E2b-] Vector for Treatment
SBC: Etubics Corporation Topic: N/ADESCRIPTION (provided by applicant): The objective of this project is to continue to develop an adenoviral vector vaccine against CEA that is effective in stimulating cell-mediated immune responses in subjects previously immune to Adenovirus. The Ad-CEA vaccine endpoint is to treat patients with CEA bearing cancers. CEA is a tumor associated protein that has been reported to be useful as a vaccin ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
New Rapid Diagnostic Tests for Amebiasis
SBC: TECHLAB, INC. Topic: N/ADESCRIPTION (provided by applicant): Our goal is to produce point-of-care diagnostic tests for amebiasis. Entamoeba histolytica is a protozoan parasite and the causative agent of amebiasis in humans. Intestinal amebiasis causes debilitating diarrhea and dysentery, while extraintestinal amebiasis occurs when the parasite migrates from the intestinal tract to organs throughout the body, most commonl ...
STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Small Molecule Blockers of B. anthracis Toxin
SBC: Innovative Biologics Inc. Topic: N/ADESCRIPTION (provided by applicant): The results from our SBIR Phase II project demonstrated that ?-cyclodextrin derivatives designed to block the transmembrane channel formed by B. anthracis protective antigen can inhibit the cytotoxic effects of anthrax toxin at low- and sub-micromolar concentrations. Several compounds were tested in vivo and showed effective protection in rats challenged with l ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Analysis of tracking based phenotypes in CNS
SBC: DRVISION TECHNOLOGIES LLC Topic: N/ADESCRIPTION (provided by applicant): Project Summary The objective of this project is to develop Prototype and Scale kinetic image recognition software to score tracking based phenotypes in a broad range of microscopy based central nervous system (CNS) applications. The target software tool can be flexibly taught to score or screen the precise dynamic phenotypes of interest, and scalable, togeth ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
QuitAdvisorMD: A point-of-care tool for brief smoking cessation interventions
SBC: SILVERCHAIR SCIENCE+COMMUNICATION, INC. Topic: N/ADESCRIPTION (provided by applicant): Primary care physicians are in a unique position to impact smoking behaviors; however, efficacy is limited due to competing demands, lack of knowledge, and lack of confidence. During Phase I of this SBIR Silverchair Science and Communications, in partnership with the University of Virginia, developed a prototype point-of-care computer software application to en ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
A Cognitive Behavioral Chronic Pain Workbook
SBC: TALARIA, INC. Topic: N/ADESCRIPTION (provided by applicant): Between 10 and 28 percent of Americans suffer from chronic low back pain (CLBP). Chronic pain self-management programs that include behavioral and cognitive-behavioral therapies (CBT) have been demonstrated as effective in improving pain, function, and quality of life. These techniques are endorsed as an important component of a comprehensive pain management ap ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
OCT Imaging of Diabetic Retinopathy in 1060nm Spectral Range (- for Diagnostic Sc
SBC: MICRON OPTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): The objective of the proposed SBIR Phase-II Competing Renewal under RFA-EY-09-001 is to develop inexpensive and compact ophthalmic instruments for rapid diabetic retinopathy (DR) detection and screening. To achieve the program objective, the key aims will be to [1] generate functional swept-source optical coherence tomography (F-SS-OCT) system at 1060nm spectra ...
SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health