Award Data

DESCRIPTION provided by applicant Alzheimerandapos s disease AD is one of the most common neurodegenerative diseases that lead to detrimental outcomes such as progressive memory deficit and cognitive impairment Although it is expected that the prevalence of AD will double over the next years currently no widely accepted molecular biomarkers for early detection or non invasive monitoring ...

PROJECT SUMMARY This proposal aims to develop a therapeutic capable of preventing and treating the severe sinus inflammation associated with chronic rhinosinusitis CRS CRS is a debilitating inflammatory disease of the sinuses that impacts over million Americans and substantially diminishes the quality of life and productivity of affected patients From to the total US health care ...

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DESCRIPTION provided by applicant The long term goal of this work is to develop an oral drug for the prevention of age related macular degeneration AMD AMD is the leading cause of blindness in the United States with million Americans diagnosed or at risk of irreversibly losing vision and over million people who already have debilitating vision loss Currently there is no FDA approved ...

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AstroPower proposes to develop gallium phosphide (GaP) ultraviolet (UV) sensors for engine combustion control. The UV spectra from the free radial combustion components correlates with combustion effectivity in terms of predetonation, and provides a real time basis for central control of excess air ratio, internal combustion temperatures, and other fuel injector parameters. A system for the engine ...

Not Available Ultra-Wideband (UWB) antennas for Unmanned Aerial Vehicles (UAVs) have been a challenge for some time, due to size and weight requirements. Such antennas can aid a number of missions in a cost-effective manner, including Synthetic Aperture Radar (SAR), Foliage Penetration (FOPEN), Ground Moving Target Indicators (GMTI) and Counter-Camouflage Concealment and Deception (CC&D). UAVs ha ...

Not Available Conducting Materials Corp. Proposes to support the antimalarial structure-based discovery efforts at Walter Reed Army Institure of Research, Division of Experimental Therapeutics. Specifically, serine hydroxymethyltransferase, an enzyme intimately linked to the metabolic functions of dihydrofolate reductase and thymidylate syntheses, will be targeted with a new generation of anti ...

The goal of this project is to develop a lightweight and compact system that provides 51 percent oxygen enriched air at four to six liters per minute equivalent pure oxygen to individuals with chronic obstructive pulmonary disease (COPD). Existing systems may not deliver a high-enough supply of oxygen to support these individuals who may be capable of activity and for whom increased activity would ...

Modern computer systems often incorporate multiple computational devices such as conventional processors, graphics processing units (GPUs), specialized accelerators, and field-programmable gate arrays (FPGAs). Programmers are able to exploit these new architectures for improved performance and reduced power consumption, but at the cost of increased programing complexity. Further complicating matte ...