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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Age-dependent Single-cell Metabolomic and Proteomic Profiling of Human Immune System

    SBC: ISOPLEXIS CORPORATION            Topic: NIA

    With this phase I submissionIsoPlexis proposes to deliver comprehensive profiling of the immune system as a measure of age dependent health in response to medical challenges or traumaThis assay will connect signaling events in the metabolome and proteome from thousands of single cells in parallel enabling the simultaneous tracking of metabolic activity and protein signaling within each immune cell ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A multivalent, easy-to-use product to mitigate and treat radiation exposure

    SBC: FIBROPLATE INC            Topic: NIAID

    ABSTRACTThe threat of radiological and nuclear accidents or attacks demands for effective radiation medical countermeasuresMCMable to mitigate and treat the effects of exposure to ionizing radiationsHematopoietic acute radiation syndromeHRASand cutaneous radiation syndromeCRSpose severelife threatening risks to exposed individualsCurrently no effective radio mitigatorto be administered after radia ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. AN ULTRA HIGH THROUGHPUT SYSTEM FOR DRUG DISCOVERY

    SBC: ANALYTICAL BIOLOGICAL SERVICES, INC.            Topic: N/A

    N/A

    SBIR Phase I 1999 Department of Health and Human Services
  4. A Single-Cell Proteomic instrument for Predictive Product Quality Check in Autologous CAR-T Immunotherapies

    SBC: ISOPLEXIS CORPORATION            Topic: 102

    While CAR-T therapies have advanced in the clinic, there are still two specific issues using these breakthrough therapies for blood cancers: Durable responses in patients are only at 30-50% and Cytokine Release Syndrome occurs in 60-90% of treated patients. These limitations, for a drug that costs as much as $500,000, may cost an additional $250,000+ for treating adverse events leading to caution ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Captioning Tools for Visual Access to Computer-Based Media

    SBC: Cap-media, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1995 Department of Education
  6. Developing, Testing and Validating a Wearable Alcohol Biosensor

    SBC: Clinitech, LLC            Topic: 450

    1 PROJECT SUMMARY2 This application for a Phase II SBIR award extends the successful completion of Phase I and represents a 3 collaboration between Clinitech, LLC and McLean Hospital/Harvard Medical School to continue the4 development of a wearable biosensor for detecting alcohol in the interstitial fluid of humans. Excessive use of5 alcohol accounts for much of the public health burden related to ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of mitoNEET agonists for the treatment of stroke

    SBC: MODULATION THERAPEUTICS, INC.            Topic: 102

    ABSTRACT Stroke is the fifth leading cause of death and the leading cause of disability in the United StatesThere remains a critical need for innovative therapeutic approaches that can successfully prevent or reverse brain injury following strokeDysfunction of the mitochondrial biochemistry following ischemic stroke and reperfusion injury contributes to significant neuronal cell losshoweverthe dev ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. DEVELOP NEW COMMERCIALLY VIABLE DEVICES, TOOLS, TECHNOLOGIES OR INTEGRATED SYSTEMS FOR DRUG DETECTION AND DEACTIVATION TO DETER OPIOID THEFT IN HOSPITALS.

    SBC: B & W TEK INC            Topic: NIDA

    The Contractorwill use modern technology to develop a fully integratedcommercially viable device for controlled pharmaceutical drug detectiondeactivationand disposal to ensure compliance with DEA regulations and deter opioid theft

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Embedded UV Combustion Sensor

    SBC: ASTROPOWER, INC.            Topic: N/A

    AstroPower proposes to develop gallium phosphide (GaP) ultraviolet (UV) sensors for engine combustion control. The UV spectra from the free radial combustion components correlates with combustion effectivity in terms of predetonation, and provides a real time basis for central control of excess air ratio, internal combustion temperatures, and other fuel injector parameters. A system for the engine ...

    SBIR Phase II 1995 Department of DefenseDefense Advanced Research Projects Agency
  10. ENHANCED DISINFECTION OF FOOD HANDLING EQUIPMENT

    SBC: COMPACT MEMBRANE SYSTEMS, INC.            Topic: N/A

    Not Available Ultra-Wideband (UWB) antennas for Unmanned Aerial Vehicles (UAVs) have been a challenge for some time, due to size and weight requirements. Such antennas can aid a number of missions in a cost-effective manner, including Synthetic Aperture Radar (SAR), Foliage Penetration (FOPEN), Ground Moving Target Indicators (GMTI) and Counter-Camouflage Concealment and Deception (CC&D). UAVs ha ...

    SBIR Phase I 1999 Department of Health and Human Services
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