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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 11740 results
  1. 3D Printed Multifunctional Brain Windows for Simultaneous Optical Imaging and Electrophysiology

    SBC: Applied Universal Dynamics, Corp.            Topic: 107

    PROJECT SUMMARY This proposal responds to PAR-18-870 titled “BRAIN Initiative: Development Optimization, and Validation of Novel Tools and Technologies for Neuroscience Research (STTR).” This project is a Fast Track STTR with a phase I and phase II. The small business, Applied Universal Dynamics Corp. (AUD) is collaborating with the University of Minnesota (U of MN). The activity patterns of t ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Implantable Peripheral Nerve Stimulator for Treatment of Phantom Limb Pain

    SBC: RIPPLE LLC            Topic: 999

    Abstract Chronic phantom limb painPLPhas been reported to inflict as many asof people with amputationsPLP is described as feeling like burningtwistingitchingor pressure in part of the missing limbThese painful sensations have a substantial negative impact on quality of lifepeople who suffer PLP have high rates of depressiondifficulty sleepingregular absences from workdissociation with family frien ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Dynasore Analogues for Ocular Surface Protection

    SBC: MEDCHEM PARTNERS LLC            Topic: NEI

    7. PROJECT SUMMARY Diseases of the ocular surface are among the top reasons for visits to eye care practitioners. These conditions can severely affect eyesight and quality of life. Symptoms may include blurry vision, discomfort or pain, redness and itching, and in severe cases, blindness due to corneal scarring. Many ocular surface diseases are initiated by loss of tear film homeostasis and can be ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced Surgical Pathology Device

    SBC: SURGIVANCE INC.            Topic: 102

    Each year, millions of Americans are diagnosed with skin cancer. The treatment with the highest cure rate and best functional and cosmetic outcomes is Mohs Surgery. Mohs depends on standard histopathology, which is slow, tedious and costly and is a 2-dimensional diagnosis, which may miss 3Dimensional information. This process is usually analog, with humans evaluating the processed tissue to determ ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC 385: POST-TREATMENT HEALTH OUTCOMES OF CANCER SURVIVORSHIP (POSTHOC)- MOONSHOT

    SBC: CHARLES RIVER ANALYTICS, INC.            Topic: NCI

    Greater prevalence of cancerespecially among the aging generationand better outcomes of cancer treatment mean that more people are living with the effects of cancer treatmentThese specialized healthcare needs can be most effectively addressed by adherence to a survivorship care planSCPThe SCP coordinates monitoring for cancer recurrencemanagement of the effects of treatmentand guidelines for healt ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Development of inhibitors of the SGK1 kinase, a critical target in anaplastic thyroid cancer

    SBC: VISIONARY PHARMACEUTICALS, INC.            Topic: 102

    ABSTRACT This Administrative Supplement is for Aim 2-1: Synthesize sufficient compound quantities to support xenograft studies. Our aims remain within the same scope of our original proposal. Unexpectedly, we found that adding a chiral center confers a great profile on our leads versus non chiral compounds. We showed that chiral leads are selective for SGK1 versus AKT1 (20-fold), active in cells ( ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Head-mounted miniature microscopes for combined calcium imaging and electrophysiological measurement of neural circuit function in deep brain regions of behaving macaques

    SBC: Inscopix, Inc.            Topic: 101

    PROJECT SUMMARY A consensus has emerged in the Neurosciences over the last decade regarding the critical importance of understanding brain function at the level of neural circuits. Such an understanding can help us bridge across scales of investigation to provide a more comprehensive model of brain function, while also providing a more direct link to the dysfunctions associated with neurological d ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. A PORTABLE MULTI-MODAL OPTICO-IMPEDANCE SYTEM FOR EARLY WARNING OF PROGRESSION IN STABLE COVID-19 PATIENTS

    SBC: MULTIVARIATE SYSTEMS INC.            Topic: NIBIB

    Project Summary / Abstract: COVID-19, the clinical presentation associated with SARS-CoV-2 infection, has already profoundly impacted healthcare systems globally. Of particular note, communities such as long-term care facilities, assisted living communities, and prisons, are being devastated because of their high density of vulnerable individuals. Nursing home residents, which represent only 0.5% ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Optical limiter based on epsilon-near-zero materials

    SBC: THIRD FLOOR MATERIALS, INC.            Topic: A18131

    The emerging class of epsilon-near-zero materials (ENZ) is a promising candidate for use in non-linear optical applications including optical limiting. The Army is soliciting proof-of-concept efforts to investigate whether limiting devices can be fabricated based on this novel class of materials. Third Floor Materials, Inc. proposes a feasibility study of such a limiting device, based on its exper ...

    SBIR Phase I 2019 Department of DefenseArmy
  10. A Novel Therapeutic Peptide to Treat P. aeruginosa Infection in Cystic Fibrosis Patients

    SBC: VIRTICI LLC            Topic: R

    Project Summary Our objective is to develop 6K-F17 as an antimicrobial agent that can be prescribed with tobramycin for the treatment of chronic, antibiotic-resistant Pseudomonas aeruginosa infection in cystic fibrosis (CF) patients. CF affects over 70,000 people worldwide1. Even with the current array of antibiotics, 80-95% of CF patients will ultimately succumb to respiratory failure brought on ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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