Award Data

Project Summary Abstract We propose a new approach to the decontamination of central venous catheters and the prevention of central line associated bloodstream infectionsCLABSIan important healthcare associated infectionCLABSIs cost the US healthcare system approximately $billion annuallyPronovostNEJMAdditionallyCLABSIs can be life threateningespecially in the very young and critically illEven whe ...

This SBIR Phase I project addresses the need to reduce the time associated with conducting tests currently used to establish targeted antibiotic (and dose) to treat infections. Sepsis and septic shock are one of the leading contributors to death in US Hospitals, responsible for 250,000 deaths annually (estimated at 30-50% of all hospital deaths). To combat these high death rates, time is of the es ...

Overmillion Americans are currently providing unpaid care to a family memberrelativeor friend with Alzheimer s disease or related dementiaWhile caregiving can be a positive experience that brings meaning and an increased sense of purposeit can also take a tollNearlyof Alzheimer s and dementia caregivers rate their emotional distress as high or very highand as many assuffer from depressionCaregiver ...

Response Technologies will attempt to qualify to MIL-DTL-27422Fs phase I performance testing criteria for thefuel cell test cubes[Class BSemi rigid or self-supporting fuel construction, Type ISelf-sealing, and Protection Level CFull self-sealing against 50 caliber and partial self-sealing against 14.5 mm] .Response Technologiesuses an additive manufacturing process that initially creates a textile ...

Response Technologies (RT) seeks to determine the technical feasibility of a: scalable, economical, repeatable, and optimized polymeric matrix (RTPM). RTPM shall have universal fuel compatibility and could replace incumbent reticulated polyurethane foams in explosion suppression fuel tanks. RT’s process utilizes additive manufacturing to produce polymeric parts from 0.5 to 20 PCF. This will be f ...

Project Abstract The goal of this Phase I SBIR is to develop a non invasive wearable dermal deviceBand Aidcapable of extracting and sensing ethanol from interstitial space using reverse iontophoresisnot sweat!and transmitting the results wirelessly to a Bluetoothcapable deviceThe proposed band aid patch will be easily applied to the epidermisand will provide monitoring of ethanol levels in a cost ...

The primary goal of this proposed research is to develop a rapid point of care test that assesses the risk of neonatal sepsisNSand or necrotizing enterocolitisNECin infants based on Inter alpha inhibitor proteinsIAIPlevels in bloodThe test is expected to be simpleuser friendlyportable and suitable for use in the NICUNS and NEC are associated with high mortality and morbidityincluding adverse neuro ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project include development of a commercial proof-of-concept percutaneous directional microwave ablation (MWA) applicator which may provide medical practitioners a new approach for treating cancer. In clinical use, a directional MWA applicator will facilitate both procedural and technical simplification of MW ...

SUMMARYShigellosisbacillary dysenteryis a severe bloody diarrhea that occurs worldwide and for which there is no licensed vaccineThis disease is particularly devastating in low income regions of the world where clean water and proper sanitation are lackingMortality and morbidity are highest in children under the age ofwith survivors exhibiting impaired growth due to malnutritionShigella sppare als ...

Pancreatic Ductal AdenocarcinomaPDACis the third leading cause of cancer related death in the United Statesand is characterized with dismal odds due to advanced disease at late stage diagnosisTheyear survival rate ranges fromfor patients with non resectable diseaseof patientstofor patients with resectable tumorsandltof patientsPDAClike most solid tumorsis highly hypoxicresulting from both poor oxy ...