Award Data

The objective of this Phase I STTR proposal is to develop a first prototype of a digital assistant to support NASA engineers in space mission engineering and design tasks in Pre-Phase A and Phase A mission studies. This technology will: 1) increase the quality and diversity of the designs explored during early stage mission concept studies; 2) decrease the time and resources it takes to perform su ...

We propose an innovative arm-mounted instrument for acquiring and analyzing planetary subsurface materials. The instrument extracts 5times;1cm cores, and immediately performs in-situ, time-resolved, coregistered imaging and spectroscopic mapping at high resolution ndash; 10micro;m and 50micro;m, respectively. Rapid analysis of cores is critical to characterize original material before it has time ...

In response to NASA SBIR FY 2018 topic A1.10, Hypersonic Technology, ThermAvant Technologies, LLC (ThermAvant) proposes to develop a high temperature, conformal thermal-mechanical leading edge skin for hypersonic aircraft. The proposed structure will provide high temperature, high heat flux acquisition and dissipation, as well as providing the structural integrity required to meet mission objectiv ...

The concept proposed is that of an innovative turbopump using hydrogen peroxide to drive the turbine. The turbopump has a unique feature in that it has an integral electric generator used to generate electricity and power an external fuel pump.By using hydrogen peroxide decomposed over a catalyst pack only one fluid can be used to drive the turbine. Typically, a turbopump combusts a fuel and an ox ...

We propose to build and critically test a TRL4 High Access Raman Probe with Onboard Optical Numerization (HARPOON), a nextgeneration ultra-compact laser Raman Spectrometer equipped with multiplexed fiber optic sensing points.HARPOON#39;s core unit, hosted inside the spacecraft, contains the laser, spectrometer, and electronic modules. The core unit serves two miniature Raman heads, which enable bo ...

PROJECT SUMMARY ABSTRACT In this Phase I SBIR applicationwe propose to develop and optimize functional Object Oriented Data AnalysisfOODAmethods and create a cloud based SaaS platform to analyze untargeted metabolomics dataUntargeted metabolomics quantifies the amount of known and unknown metabolites in samples with the purpose of finding known and unknown metabolites that correlate with subgroups ...

PROJECT SUMMARYDespite recent advances in cancer therapiesplatinum based drugs are still widely used for the treatment of solid tumorsA primary example is cisplatinwhich is frequently used to treat lungbladdertesticularand cervical cancersHoweverlimitations of this therapy include the development of drug resistance in cancer cells as well as severe side effectssuch as nephrotoxicity and neurotoxic ...

ABSTRACT Human leukocyte antigenHLAtyping is an essential laboratory test to evaluate the donor recipient compatibility before life saving transplantationsInaloneHLA typing of donors and recipients guided overorgan and stem cell transplantations in the United StatesExisting high resolution HLA typing methods require a turnaround time of days to weeksThere has been an unmet clinical need for a rapi ...

PROJECT SUMMARY ABSTRACT Chikungunya virusCHIKVis a mosquito transmitted alphavirus that causes explosive epidemics of a severe febrile illness characterized by debilitating polyarthralgia in humansCHIKV caused an estimatedmillion new cases in India alone inand has the potential to spread globally because of the distribution and abundance of its mosquito vectorsAedes aegypti and Aedes albopictusDu ...

Cancer is thend leading cause of death in the United StatesUSand accounts forof everydeathsMore thanAmericans will die of cancer inwith annual US cancer care expenditures reaching $B byand more thanM cancer related deaths occur annuallyWhile chemotherapy is effectiveseveral cancer subtypesincluding liver cancerare associated with a very lowyear survival rate of less thanIn additiononly a small pro ...