Award Data

Recent developments in the world political arena have led to The need for miniaturized instrumentation for rapid characterization of micro-organisms and toxins to protect military and civilian personnel against biological weapons and to allow timely administration of prophylactics. Considerable effort is currently underway to develop polymerase chain reaction (PCR) assays with automated samp ...

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Chesapeake PERL is a contract manufacturing company using the baculovirus expression system for mass production of proteins in lepidopterous insect larvae. PERL's automated in-line insect mass rearing and inoculation systems enables the production oflarge quantities of complex, biologically fully functional proteins. The baculovirus expression system as developed in the eighties and nineties is ...

There is an immediate need for real-time sensitive and selective detection of biological warfare agents (BWA) in air or water. Essential components of developmental biological and chemical sensors are the molecular receptors or recognition elements.Molecular imprinting of polymers has been used with promising results to create artificial chemical receptors. Echo Technologies, Inc. proposes to de ...

THE CONTRACTOR HAS PATENTED TECHNOLOGY FOR A UNIQUE PROCESS THAT DIRECTLY CONVERTS AN ACOUSTIC SIGNAL INTO A VISIBLE ONE IN REAL-TIME WITHOUT ELECTRONIC CIRCUITRY. THIS RELIES ON THE ACOUSTO-OPTICAL PROPERTIES OF A CONTINUOUS LAYER OF LIQUID CRYSTAL THIN FILM LAYER WHICH SERVES AS BOTH THE SENSOR AND THE DISPLAY. THE IMAGE CAN BE VIEWED DIRECTLY BY MEANS OF CCD CAMERA. HOLOGRAPHY PROVIDES FOR BOTH ...

The ability to detect minute quantities of toxic biological substance s will provide the ability to quickly assess a situation so that an a ppropriate response to exposure can be orchestrated. Not only will t he development of this technology be important in toxic agent warfare detection, the biological sensors would be pertinent in commercial ap plications such as process control and point-of-ca ...

The ability to develop new technology on the basis of existing commercial technology can offer significant cost savings when compared to research programs to develop new technology from scratch. Continuing developments in mass spectrometry (MS), vacuum Systems and high speed gas chromatography (GC) sampling and analysis methods, have created an opportunity to fully demonstrate a powerful handporta ...

Large X-ray generators using gas fill loads are a key element in the DTRA simulator program. Consistent relative timing between the injection of the gas shell and the generator current pulse is crucial to producing consistent, high-yield x-ray pulses.To that end HY-Tech proposes replacing existing high voltage trigger pin technology, with a sensitive, all fiber-optic heterodyne interferometer ba ...

Besides performing a thorough statistical analysis of the government furnished data sets to determine the features and metrics for spectral unmixing, Intelligent Automation, Inc. and Prof. C. Chang of University of Maryland at Baltimore County also proposean innovative approach to detect and classify chemical and biological agents. There are two major steps. First, we propose to apply a recently d ...

Suspended or reduced animation of brain and heart tissues during battle-field injury or during critical-care trauma may result in a significant protection from organ damage, systemic shock, and pain and may provide a prolonged window of opportunity fortreatment. Suspended or reduced animation of brain and heart tissues may be achieved by a complete suspension or suppression of neural activities ( ...