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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Drop Out Computer Training Options Research (DOCTOR) CD Rom Products Development

    SBC: SYSTEMS ENGINEERING ASSOCIATES CORPORATION            Topic: N/A

    N/A

    SBIR Phase I 1998 Department of Education
  2. Engineered Spores as Fluorogenic Biological Indicators for Sterility Testing

    SBC: BCR DIAGNOSTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): BCR Diagnostics, Inc. (BCR) has recently developed and patented a technology platform for engineering fluorogenic functionality into living Bacillus spores. Fluorogenic spores (F-spores) produced at BCR appear to be physiologically identical to normal spores except for performing as self-reporters of initial germination events. ...

    SBIR Phase I 2007 Department of Health and Human Services
  3. ENCAPSULATED TRANSFECTED CELLS AS A THERAPY FOR MS

    SBC: Cytotherapeutics, Inc.            Topic: N/A

    N/A

    STTR Phase I 1998 Department of Health and Human Services
  4. Optimization of a Multivalent Tuberculosis Vaccine

    SBC: EPIVAX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This new Phase I SBIR proposal addresses the continuing worldwide need for a tuberculosis (TB) vaccine. We detail a novel multivalent strategy that aims to elicit immunity to prevent reactivation of latent TB. This epitope-driven, DNA-prime, protein-boost TB vaccine has been in development since 1997, when our immunoinformatics tools were first applied to ident ...

    SBIR Phase I 2007 Department of Health and Human Services
  5. Epitope-driven deimmunization of Factor VIII

    SBC: EPIVAX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Hemophilia A patients are prone to develop inhibitory immune responses to the very therapy they require: Factor VIII protein replacement. Up to 30% of all hemophiliacs and greater than 50% of severe hemophiliacs produce antibodies (inhibitors) in response to treatment. Immunogenicity to Factor VIII (FVIII) is its most significant complication: immunogenicity no ...

    SBIR Phase I 2007 Department of Health and Human Services
  6. Data Documentation Database (D3): An Essential Research Tool

    SBC: MJ Datacorp, Ltd.            Topic: N/A

    DESCRIPTION (provided by applicant): SBIR Abstract for DATACORP's Data Documentation Database (D3) Data documentation is an intricate and time-consuming task. Practical experience has shown that research studies frequently save time and financial costs by delegating the task to less experienced staff or by incompletely documenting the data. Yet poor documentation threatens the data's integrity, le ...

    SBIR Phase I 2007 Department of Health and Human Services
  7. High Content Screening for Muscular Dystrophy

    SBC: MYOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Myomics' drug screening technology to be developed in this Phase 1 SBIR project for Duchene muscular dystrophy (DMD) is based upon an in vitro skeletal muscle tissue force measurement technique for high content screening (HCS) of compounds to attenuate muscle weakness. Currently, there are few drugs besides Prednisone which are used clinically to slow muscle we ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. Hybridization-Assisted Nanopore Sequencing

    SBC: NABSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The rationales for the development of technology that will enable extremely cheap, high speed sequencing are well established. Chief among these is the enablement of personalized medicine. There are currently in development several technologies that promise to markedly decrease the cost of sequencing a human genome. It is unclear, however, that any of these wil ...

    SBIR Phase I 2007 Department of Health and Human Services
  9. Promoting Health During Pregnancy: A Multiple Behavior Expert System Intervention

    SBC: Pro-Change Behavior Systems Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Low birthweight and preterm birth are unfavorable birth outcomes that translate into serious and costly health issues, including infant morbidity and infant mortality. Research demonstrates that the health behaviors of pregnant women are associated with not only birth outcomes, but also the future health of the child. The goal of this research is to develop an ...

    SBIR Phase I 2007 Department of Health and Human Services
  10. Bioprocessing of Plasma Therapeutic Proteins using Sequential Affinity Monolithic

    SBC: PROTHERA BIOLOGICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Plasma fractionation is one of the largest industry segments in global therapeutic protein manufacture. The United States plays an important role in this industry since it represents the largest plasma collection and manufacturing base that accounts for more than 50% of the world supply of plasma. Even though more than 22 million liters of plasma are collected ...

    SBIR Phase I 2007 Department of Health and Human Services

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