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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. High throughput Electrophysiological Purification Array HEPA for cell based therapies

    SBC: BIOPICO SYSTEMS Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant High throughput Electrophysiological Purification Array HEPA for cell based therapies Abstract Patient specific reprogrammed somatic cells induced pluripotent stem cells or iPSCs have raised hope for revolutionary regenerative treatments for heart lung and blood diseases and drug development applications For example these iPS cells can be differentiated ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Development of OCT Imaging Adapter for Interstitial Tissue Imaging

    SBC: WEST FACE MEDICAL DEVICES, INC.            Topic: NIBIB

    DESCRIPTION provided by applicant This Phase I STTR Grant Proposal requests $ support for WestFace Medical Device to construct and test the WestFace Imaging Adaptor in conjunction with Ruikang K Wang PhD and his laboratory at the University of Washington Utilizing optical coherence tomography OCT the patented OCT Adaptor USPTO Pats provides r ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. rAAV5-hCNGB3 Gene Therapy for Achromatopsia: Safety and Efficacy in a Dog Model

    SBC: APPLIED GENETIC TECHNOLOGIES CORPORATION            Topic: N

    DESCRIPTION provided by applicant Complete achromatopsia is an autosomal recessive inherited congenital disorder of retinal cone photoreceptors Patients with complete achromatopsia experience extreme light sensitivity and daytime blindness and best visual acuity under non bright light conditions is usually or worse and generally stable over time In addition to poor acuity hypersensit ...

    STTR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Cell Lysates to Sequencing Reads: A Multiplex Gene Expression Profiling Tool for

    SBC: BioSpyder Technologies, Inc.            Topic: 172

    DESCRIPTION provided by applicant This proposed Phase I SBIR project will transfer RASL Seq a targeted sequencing technology developed in academia to a small business Xpress Inc and demonstrate feasibility for its commercialization as a platform for drug discovery and high throughput screening HTS The technology detects hundreds of RNA targets at once in cell lysates using oligo li ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Training Attentional Awareness and Control in ADHD

    SBC: THINK NOW INCORPORATED            Topic: NIMH

    DESCRIPTION provided by applicant Attention Deficit Hyperactivity Disorder ADHD is a highly prevalent disorder incurring billions of dollars of costs annually for which there is a rel need for additional non pharmacologic treatments Deficits in maintaining attentional control manifest as inconsistent intra individual performance on sustained attention tasks with periods of normal performan ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. THIS SBIR PHASE I CONTRACT IS FOR A WEARABLE ALCOHOL BIOSENSOR THAT QUANTIFIES BAC IN REAL TIME.

    SBC: DeLeon, Augustina S            Topic: NIAAA

    Technology validation study of a wearable NIR spectrometer to quantify BAC in real time

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. SBIR PHASE I- WEARABLE BIOSENSOR THAT QUANTIFIES BLOOD ALCOHOL CONCENTRATION IN REAL TIME

    SBC: SUGPIAT DEFENSE, LLC            Topic: NIAAA

    Testing Bio Sole biosensor as a wearable technology to quantify BAC in real time

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. SBIR TOPIC 108, FAST-TRACK- DEVICE SYSTEM FOR TRANSCATHETER REPAIR OF POSTINFARCTION VENTRICULAR SEPTAL DEFECT

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    The goal of the project is to develop a device for percutaneous closure of postinfarction ventricular septal defectVSDin adultsFirst a prototype would be developed and tested in animalsand ultimately a clinical grade device would undergo regulatory developmentPhase I will include the development and testing of a postinfarction VSD occluder prototypePhase II will include mechanical and safety testi ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. SBIR TOPIC 106, FAST-TRACK- ACTIVE MRI NEEDLE

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    Needle access to deep organs is common to numerous catheterradiologicaland surgical proceduresboth diagnostic and therapeuticincluding access to blood vesselspericardial and cardiac chambersvisceraetcMRI operation affords exquisite imaging and delineation of soft tissue beyond what is afforded by X ray fluoroscopyCTand ultrasound guidancePassiveneedles visualized solely by their material propertie ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. SBIR TOPIC 107, PHASE I- TRANSCATHETER POTTS SHUNT

    SBC: TRANSMURAL SYSTEMS LLC            Topic: NHLBI

    The goal of Phase I is to develop and test a Transcatheter Potts Shunt prototype system in vivoThe deliverable is a catheter system to establish a non surgical Potts Shunttranscatheter pulmonary to aortic anastomosisto treat refractory pulmonary artery hypertensionPhase I will focus on mechanical and biological performance of the proposed endografttaking into account mechanical strength required f ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health

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