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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A2a Adenosine Receptors and Equine Sepsis

    SBC: ADENOSINE THERAPEUTICS, LLC            Topic: N/A

    NON-TECHNICAL SUMMARY: This is a phase I SBIR proposal by Adenosine Therapeutics for 6 months of support to synthesize and evaluate novel compounds as agonists of equine A2A adenosine receptors. Some of these compounds have been found to be very effective in reducing rodent mortality form endotoxin or from E. coli-induced sepsis. Circulating endotoxin (lipopolysaccharide) is correlated with the pr ...

    SBIR Phase I 2003 Department of Agriculture
  2. A Bread Based Environment for Test (ABBET) Architecture Prototype

    SBC: QUINCY STREET CORP.            Topic: N/A

    The overall abjective of this proposed project is the development of detailed definitions for the interfaces defined by the ABBET architecture. Signal models wil developed based upon the C/ATLAS set of signal nouns. A Test Foundation Framework (TFF) will be implemented to demonstrate the ability of test program or test program component transfer across multiple test platforms. This phase also w ...

    SBIR Phase I 1998 Department of DefenseAir Force
  3. Accelerated Lattice Boltzmann-Monte Carlo Method for Simulation of Rarefied Material Dynamics

    SBC: INFORMATION SYSTEMS LABORATORIES INC            Topic: N/A

    The feasibility of a new approach that will accelerate the modeling of problems involving rarefied gas dynamics is established. The proposed hybrid approach solves the Boltzmann equation directly using a carefully designed discrete-velocity model and adiscrete Monte Carlo collision process with several extensions that accelerates its computational capability in comparison with direct simulation M ...

    SBIR Phase I 2003 Department of DefenseDefense Advanced Research Projects Agency
  4. ACCESSIBLE GRAPHING SCIENTIFIC INTERACTIVE CALCULATOR

    SBC: Automated Functions, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Many high schools use a graphing scientific calculator to assist students in math and science courses. These calculators have a built-in screen and displays graphs and perform scientific functions. These calculators are used widely in higher math (Algebra I and beyond) and science courses. They are a valuable tool for high school teachers and students. Unfor ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. A Clinical Trial Enrichment Tool Based on Subgroups Defined by Machine Learning Predictive Models

    SBC: ORIGENT DATA SCIENCES, INC.            Topic: 102

    ABSTRACT Neurodegenerative disordersincluding amyotrophic lateral sclerosisALSFriedreichandapos s ataxiaFAmultiple sclerosisMSDuchenne muscular dystrophyDMDAlzheimer s diseaseADParkinson s diseasePDand Huntington s diseaseHDare characterized by heterogeneous disease progressionEfforts to identify responder subgroups may uncover subgroups that are more homogeneous in disease related features than t ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. A cloud-based WGS platform for establishing phylogeny within epidemic outbreaks at hospitals

    SBC: ICBiome            Topic: NIAID

    Outbreaks have become a significant public threat in hospitalsimpacting both patient lives and creating a financial burdenWith the increasing rise in antibiotic resistancenew interventions are urgently needed to contain ongoing outbreaksRecent studies have confirmed that whole genome sequencingWGSis able to identity unique mutations within each outbreak strainwhich can then be utilized to establis ...

    SBIR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. A Code Analysis Tool for High-Integrity Systems

    SBC: DCS CORP.            Topic: N/A

    Research is currently underway to produce guidelines for the development of mission and safety critical systems implemented in Ada 95. This research will analyze whether certain features of Ada 95 should be included or excluded from a critical application. To be of practical value such an analysis will require specific tool support. The Ada Semantic Interface Specification (ASIS) defines a ...

    SBIR Phase I 1998 Department of DefenseNavy
  8. 8a: Comprehensive Enzyme Stabilization for Cell-Free Bioproduction

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: 08a

    Bioproduction is typically reliant on host-organisms to express the enzymes needed for a synthetic pathway, which suffers from drawbacks like wasted metabolic resources, feedstock toxicity, and purification. Cell-free bioproduction is the logical alternative, but one major drawback is stability of the enzymes in the absence of a cell. For cell-free bioproduction to be feasible, enzymes will need t ...

    SBIR Phase I 2019 Department of Energy
  9. A COMPREHENSIVE PROGRAM TO DESIGN HIGH PERFORMANCE AND HIGH EFFICIENCY AGRICULTURAL VENTILATION SYSTEMS

    SBC: Digital Flow Technologies, Inc            Topic: N/A

    Tunnel ventilation is an effective means of protecting and enhancing the productivity of livestock (especially swine and egg layers) in large scale confinement barns. The capital and operating costs for these fan installations typically represents a significant fraction of the total costs to the livestock producer. The Phase I research program has shown that significant improvements (ca. 40 perce ...

    SBIR Phase I 1998 Department of Agriculture
  10. A Compreshensive Approach to the Development of Multivehicle Aerodynamics Simulation Models

    SBC: BIHRLE APPLIED RESEARCH INC            Topic: N/A

    The development of control laws for control of UCAVs in formation requires knowledge of the complete multivehicle dynamical system. This Phase I effort focuses on the design and development of simulation models for multiUCAV situations. During the primary work phase of this effort, a limited wind-tunnel entry in the Langley Full-Scale Wind Tunnel will be performed to demonstrate the ability to m ...

    SBIR Phase I 1998 Department of DefenseAir Force
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