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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Operational Outer Zone Energetic Charged Particle Model

    SBC: ADVANCED RESEARCH CORPORATION            Topic: AF17CT03

    Earths outer radiation belt, which consists of electrons with hundreds of keV to MeV energies, is a highly dynamic and driven environment.The large variations in electron flux, if unaccounted for, can cause satellites that travel through this complex region to experience anomalous behavior ranging from temporary satellite outages due to electrostatic discharge events in system electronics to poten ...

    STTR Phase I 2018 Department of DefenseAir Force
  2. Low-cost production of ultra-low defect GaN-based power electronics

    SBC: Qrona Technologies LLC            Topic: N18AT004

    GaN power semiconductors offer a technological breakthrough for improving the performance of power electronics including power density, conversion efficiency, and reliability of power converters. These are the three most critical requirements for military, aerospace and many commercial applications. In this STTR program, Qrona Technologies will collaborate with the University of Central Florida to ...

    STTR Phase I 2018 Department of DefenseNavy
  3. CPS: Creative Problem Solver

    SBC: Smart Information Flow Technologies, LLC            Topic: N16AT002

    Military systems operate in complex, adversarial environments where their initial planned operations are often overcome by events, but soldiers use those systems in creative ways to achieve their mission objectives. For example, complex ground robotic systems that were initially deployed for surveillance and explosive ordinance disposal have instead been used as decoys, ammunition carriers, and ot ...

    STTR Phase II 2018 Department of DefenseDefense Advanced Research Projects Agency
  4. Plug-In Hybrid Vehicle Optimization Using Vehicle-to-Cloud Connectivity

    SBC: Macchina, LLC            Topic: 13c

    Plug-in hybrid electric vehicles (PHEVs) represent a growing segment of the U.S. passenger vehicle market. An increasing number of PHEV models are available to consumers. PHEVs are similar to parallel hybrid vehicles like the Toyota Prius in that they have an electric motor and internal combustion engine that are used synergistically to significantly reduce fuel consumption while maintaining a nea ...

    STTR Phase I 2018 Department of Energy
  5. Nucleobase aminosugars with reduced ototoxicity

    SBC: NUBAD, LLC            Topic: Y

    PROJECT SUMMARYAminoglycosides are one of the cheapest and well known antibiotics in clinical use for overyearsbut one of the major limitations in their use is their ototoxicityWe are developing fast and low cost methods to develop aminoglycosides with antiribosomal activities and reduced toxicityIn this projectwe will identify novel aminoglycoside antibacterialsthat show reduced ototoxicityComple ...

    STTR Phase I 2018 Department of Health and Human Services
  6. Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma

    SBC: Leukogene Therapeutics Inc.            Topic: 102

    Project Summary Abstract Multiple MyelomaMMis the second most common form of blood cancer and remains an incurable and deadly diseaseProteasome inhibitorPItherapy is a cornerstone in the treatment of MMbut resistance to this class of agent is an emerging challenge in the clinicNew therapeutic approaches that specifically target resistance are needed to maximize responses and ultimately produce cur ...

    STTR Phase II 2018 Department of Health and Human Services
  7. Robot-Assisted Cognitive Training for Socially Isolated Older Adults with Mild Cognitive Impairment

    SBC: Applied Universal Dynamics, Corp.            Topic: NIA

    Project Summary Abstract This project will develop a Socially Assistive RobotSARto provide cognitive trainingin the form of learning to play the pianoto improve cognitive functioning and reduce feelings of loneliness in socially isolated older adultsThe SAR will administer cognitive training via guided practice on a set of standard piano lesson tasks designed to reflect particular cognitive functi ...

    STTR Phase I 2018 Department of Health and Human Services
  8. Validation of a Novel Fungicidal Approach for Cryptococcal Meningitis

    SBC: Minnetronix Medical, Inc.            Topic: NIAID

    ABSTRACT When Cryptococcus is manifested as cryptococcal meningitisCMit creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treatThere are now an estimatedUS cases andcases of CM worldwide annuallywith estimated mortality ofper yearCM is caused when Cryptococcus neoformansa basidiomycete fungal pathogeninvades the central nervous systemCNSIt ...

    STTR Phase II 2018 Department of Health and Human Services
  9. Validation of Novel Therapeutic Approach for Leptomeningeal Metastases

    SBC: Minnetronix Medical, Inc.            Topic: 102

    ABSTRACT Leptomeningeal MetastasesLMis a condition in which tumor cells from a primary tumor metastasizeinvade the subarachnoid spaceSASand spread throughout the cerebrospinal fluidCSFresulting in seeding along the meningesbrain and spinal cordLM represents a devastating event of cancer progressionThere arecases annually and currently no curewith average survival ofmonths with current therapiesRed ...

    STTR Phase II 2018 Department of Health and Human Services
  10. Development of mitochondrial disease mouse models

    SBC: B-MoGen Biotechnologies Inc            Topic: OD

    Project Abstract Mitochondria are double membrane bound organelles that are found in all eukaryotic cells and carry a specialized circularkb genomeThere is a group of devastating human genetic diseases caused by inherited or spontaneous mutation of genes encoded within the mitochondrial genomeThese diseases can cause a wide array of medical problems from subtle muscular weakness to extreme neuromu ...

    STTR Phase I 2018 Department of Health and Human Services

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