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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Enhancing Homologous Recombination in Plants Through the Use of Custom Endonucleases

    SBC: Advanced Genome Technologies, Llc            Topic: 48

    Homologous recombination (HR) permits the precise insertion, deletion, or substitution of genetic material in the genome of an organism. HR offers numerous opportunities for modifying plant genomes to enhance our understanding of plant gene function and regulation, especially with respect to enhancing the production of biofuels. Although HR normally occurs at very low frequencies, approximately ...

    SBIR Phase I 2007 Department of Energy
  2. Physiological-based Tools for Virtual Environment Fidelity Design Guidance

    SBC: ADVANCED INFONEERING, INC.            Topic: N07T028

    We propose to use physiological sensors to measure the quality of a trainee's interaction with a virtual environment (VE) as a function of VE fidelity to enable design improvements in VEs and to enhance training effectiveness through feedback of physiological-based performance information. Currently, VE design is guided by subjective design models that involve multiple design iterations and focus ...

    STTR Phase I 2007 Department of DefenseNavy
  3. SBIR Phase I: Ultra-High Powered Lasers: Lanthanide Oxide Single Crystals as a New Light Source

    SBC: ADVANCED PHOTONIC CRYSTALS, LLC            Topic: EL

    This Small Business Innovation Research Phase I project will prove out the concept that appropriately doped single crystals of lanthanide oxides (i.e. Yb:Sc2O3) can be grown via a commercially viable hydrothermal process. These crystals will enable the development of new high powered diode pumped solid state lasers with cw powers in kilowatts and pulse operations to 200 femtoseconds. The use of do ...

    SBIR Phase I 2007 National Science Foundation
  4. Noninvasive Nocturnal Hypoglycemic Alarm

    SBC: ASL Analytical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A collaborative effort between ASL Analytical, Inc. and a research team at the University of Iowa is proposed to development a noninvasive nocturnal hypoglycemic alarm. The goal for the alarm system is to provide continuous noninvasive measurements during the sleep period of an individual with diabetes, sounding an audible alarm to wake the person if an impe ...

    STTR Phase I 2007 Department of Health and Human Services
  5. Enhancing Pork Quality and Value Using Live Animal Ultrasound Technology for Better Breeding and Marketing Decisions

    SBC: BIOTRONICS, INC            Topic: N/A

    Consumers and an ever growing segment of the pork industry know that more optimal levels of marbling must be put back into the high-value pork cuts. Biotronics, Inc. is developing technology to solve this problem by using real-time ultrasound to measure the percent of intramuscular (% IMF) fat in live pigs and hot carcasses. The premise of the project is that swine breeders can be rewarded financi ...

    SBIR Phase II 2007 Department of Agriculture
  6. Commercial Feasibility Assessment of Pancreatic Islet Progenitor Cell Technology

    SBC: Cell & Tissue Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The ability of islet transplantation to reproducibly reverse diabetes for extended periods has been demonstrated in recent clinical studies. However the need for 2-3 donor organs per transplant means that less than 1% of the insulin-dependent diabetes (IDDM) population could be treated with this protocol. The ultimate objective of this proposal is focused on th ...

    SBIR Phase I 2007 Department of Health and Human Services
  7. New Solutions Islet Recovery Preservation of Pancreas

    SBC: Cell & Tissue Systems, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Transplantation of islets of Langerhans for the clinical treatment of Type I diabetes has had a resurgence of interest due to results obtained using the "Edmonton protocol". However, at this time, procurement of donor pancreases for islet isolation and transplantation is in its infancy. Most pancreases at more remote donor sites are not procured due to justifie ...

    SBIR Phase II 2007 Department of Health and Human Services
  8. Double-tuned Cryogenic Imaging Platforms for Pre-clinical MRS

    SBC: DOTY SCIENTIFIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop a series of ultra-high-performance, double-tuned, cryogenic, cost-effective, MRI rf coil platforms, especially for improved MR spectroscopy (MRS) in pre-clinical studies in small animals at high-fields. Substantial gains in S/N appear likely for a wide range of pre-clinical, single- organ, MRS applications, both single-re ...

    SBIR Phase I 2007 Department of Health and Human Services
  9. AN ULTRA-HIGH-POWER H/C/N NMR PROBE FOR MEMBRANE PROTEINS

    SBC: DOTY SCIENTIFIC, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Available methods for molecular structure determination, based primarily on x-ray crystallography and Nuclear Magnetic Resonance (NMR) solution methods, have had limited success on the insoluble proteins that are critical to bio- logical function. Various recent developments have enhanced the effectiveness of solids NMR methods incorporating Magic Angle sample ...

    SBIR Phase I 2007 Department of Health and Human Services
  10. High Frequency Broadband Hybrid Transducer/Amplifier

    SBC: Etrema Products, Inc.            Topic: N07075

    The proposed development will result in a compact, efficient, broadband transducer module including amplifier and wet-end transducer. To facilitate multiple mission requirements, the transducer performance goals are a broad bandwidth (7-30 kHz), compact size on the order of 1/2 wavelength at the center frequency, at least 30 watts output power, and high efficiency. The resulting technology from ...

    SBIR Phase I 2007 Department of DefenseNavy

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