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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  3. Practical Multi-Step Turbulent-Combustion Model for Fuel-Flexible Gas

    SBC: CFD Research Corporation            Topic: 55c

    DOE¿s FutureGen Initiative involves the development and demonstration of fuel-flexible gas turbine combustors that burn fuels with high hydrogen concentrations (e.g. syngas or pure hydrogen). Combustion goals include high efficiency and low emissions (NOx < 2 ppmv). Advanced Large Eddy Simulation (LES) analysis is expected to play an important role in developing fuel-flexible combustion technolog ...

    SBIR Phase I 2008 Department of Energy
  4. Neodymium-Containing Single Crystals for Neutrinoless Double Beta Decay Detection

    SBC: Integrated Photonics, Inc.            Topic: 37b

    The Neutrinoless Double Beta Decay Underground Detector has been identified by DOE as a high scientific priority. Unfortunately, the current generation of proposed experiments to determine neutrino mass would require 500 kg of germanium (Ge) that is isotopically enriched to 86% in 76Ge. The cost of this specialized Ge would exceed $100 million. 150Nd is an alternate parent isotope for neutrinoless ...

    SBIR Phase I 2008 Department of Energy
  5. Electrochemical Microalloying of Tungsten for Plasma Facing Component Applications

    SBC: Plasma Processes, LLC            Topic: 31a

    Tungsten and its alloys are candidates for plasma-facing-component heat sinks and armor used in fusion energy systems, due to their low sputtering rate, high melting point, high thermal conductivity, high strength at elevated temperatures, and low tritium inventory. However, tungsten¿s inherent low ductility makes it difficult to fabricate plasma facing components and limits its use as a struct ...

    SBIR Phase I 2008 Department of Energy
  6. Remote Sensing through Imaging Polarimetry for Nuclear Non-Proliferation

    SBC: Polaris Sensor Technologies, Inc.            Topic: 44a

    Remote sensing technologies are used to identify activities associated with the proliferation of weapons of mass destruction. Remote sensing requires the extraction of as much information as possible from the available measured energy, in order to identify objects of interest in the scene. Polarization is a fundamental property of light that is not typically exploited because of the additional dif ...

    SBIR Phase I 2008 Department of Energy
  7. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  8. Enhancing Homologous Recombination in Plants Through the Use of Custom Endonucleases

    SBC: Advanced Genome Technologies, Llc            Topic: 48

    Homologous recombination (HR) permits the precise insertion, deletion, or substitution of genetic material in the genome of an organism. HR offers numerous opportunities for modifying plant genomes to enhance our understanding of plant gene function and regulation, especially with respect to enhancing the production of biofuels. Although HR normally occurs at very low frequencies, approximately ...

    SBIR Phase I 2007 Department of Energy
  9. Reducing the Effective Filament Diameter of Niobium-Tin Superconductors

    SBC: Alabama Cryogenic Engineering, Inc.            Topic: 33

    Niobium tin superconductors have had large improvements in current density over the past few years. However, the effective filament diameters of these conductors are too large, which can limit their application in areas such as High Energy Physics Colliders, Fusion Devices, and laboratory electromagnets. The filament diameter limits have been shown to be caused by fundaments limits in the cold d ...

    SBIR Phase I 2007 Department of Energy
  10. Tungsten Alloy Divertor Concept with Helium Jet Cooling

    SBC: Plasma Processes, LLC            Topic: 34

    Helium-cooled, refractory metal heat sinks are being considered for the divertor sections of several fusion energy reactors. One type of helium cooling, jet impingement, has shown promise for high heat flux applications. However, because of the small size of the units (1.5-2 cm), a large number of these heat sinks would be needed for the divertor section of a reactor. Recently, a mid-size heliu ...

    SBIR Phase II 2007 Department of Energy

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