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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Nanotechnology-Enhanced Sensor for Toxic Industrial Chemicals

    SBC: STREAMLINE AUTOMATION, LLC            Topic: SB072001

    Chlorine gas was first used as a weapon during World War I and has reemerged as a threat in Iraq compounding the dangers from existing improvised explosive devices. One of the significant challenges with preventing attacks that involve toxic industrial chemicals (TICs) like chlorine, ammonia is that they have genuine civilian uses for water treatment, in refrigeration systems, and others, that m ...

    SBIR Phase I 2008 Department of DefenseDefense Advanced Research Projects Agency
  3. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. Novel Nanofluidics-Based Sensor System

    SBC: CFD Research Corporation            Topic: SB062001

    We propose to develop a nanofluidics-based biosensor system for detection and quantitation of biological threat agents. The proposed system will harness the potential of recently discovered nanofluidic phenomena, not possible in microfluidic/capillary systems, to enhance rapid and sensitive sample preparation and detection. Specifically, we will develop a nanofluidics-based device to separate and ...

    SBIR Phase II 2008 Department of DefenseDefense Advanced Research Projects Agency
  5. Optically Reflecting Flexible Membrane

    SBC: DIGITAL FUSION SOLUTIONS, INC.            Topic: SB072036

    Military imaging optics, such as rifle scopes, spotter scopes, and optics found on unmanned vehicles could be substantially better if the mechanical movement of optics for focus and zoom could be eliminated, without creating new problems associated with the rugged and harsh environment. The technology of liquid lenses has surfaced as a possible solution, but these lenses have problems with enviro ...

    SBIR Phase I 2008 Department of DefenseDefense Advanced Research Projects Agency
  6. Metamaterials Lens

    SBC: DMS Technology, Inc.            Topic: SB072035

    We provide a novel approach to realizing negative index lenses and lenslet arrays at optical frequencies using a naturally occurring material such as cis-vitamin A, a constituent in some commercially available cod-liver oils. This form of vitamin A has been recently found in the eyes of lobsters and hypothesized to be responsible for negative index lensing in their superposition eyes. The propos ...

    SBIR Phase I 2008 Department of DefenseDefense Advanced Research Projects Agency
  7. Sparse Array Applications for Small Satellites

    SBC: TIME DOMAIN CORP.            Topic: SB062020

    The purpose of this program is to provide a technology that enables the deployment of constellations of satellite based, coherent, RF sparse arrays. Such sparse arrays would have higher resolution than conventional approaches and would provide superior remote sensing capabilities at a fraction of today’s cost. The key enabling mechanisms are 1) the ability to accurately measure the distance be ...

    SBIR Phase II 2008 Department of DefenseDefense Advanced Research Projects Agency
  8. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  9. Nanoelectrokinetic, Label-free Sensor for Toxic Industrial Chemical Detection

    SBC: CFD Research Corporation            Topic: SB072001

    We propose to develop a novel nanofluidic, label-free sensor to detect the presence of ultra-low levels of Toxic Industrial Chemicals (TICs) in aqueous environmental samples. The envisioned handheld sensor will be hand-portable, be ruggedly constructed, support remote operation and be UAV-mountable. Our sensor exploits novel features of AC electrokinetics, made possible only when the channel dimen ...

    SBIR Phase I 2007 Department of DefenseDefense Advanced Research Projects Agency
  10. Design of Negative Index Metamaterials for the Visible Spectrum

    SBC: DIGITAL FUSION SOLUTIONS, INC.            Topic: SB072035

    Optical imaging systems are used extensively in everyday life for military and civilian applications. Just like any other technology there is always a push to improve the performance over what is the current state of the art. Unfortunately, all optical systems are constrained by the fundamental limit of diffraction. This constraint limits the resolution of a system to approximately half of the ...

    SBIR Phase I 2007 Department of DefenseDefense Advanced Research Projects Agency

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