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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Handheld IR Raman Spectroscopy for Rapid Chemical Identification

    SBC: Aerius Photonics, LLC.            Topic: CBD08102

    Aerius Photonics and partner Ahura Scientific, propose to develop a handheld system, based on Ahura’s successful FirstDefender Raman system, that employs an excitation laser emitting at 980 nm and a low noise InGaAs array based on Aerius’ high performance InGaAs technology. This system will substantially reduce the fluorescence present in CCD-based systems, and unmask otherwise obscured spect ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  2. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  3. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  4. Dynamic Multicomponent Optical Analyzer for Chemical Weapon (CW) Exposure Studies

    SBC: Los Gatos Research            Topic: CBD08104

    In this SBIR Phase I effort, Los Gatos Research (LGR) proposes to design, develop and test a novel laser-based gas analyzer optimized for chemical weapon exposure studies based on cavity enhanced absorption in the mid-infrared spectral region. This analyzer will provide sensitive and accurate quantification of several chemical weapons through real-time measurements of high-resolution absorption s ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  5. Combined Dielectrophoretic Microfluidic System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD08101

    To address the U.S. Army CBD need for a high resolution system whereby proteins present in a complex mixture can be rapidly and reproducibly separated, Physical Optics Corporation (POC) proposes to develop a new Combined Dielectrophoretic Microfluidic (CDM) System based on the integration of electrodeless dielectrophoresis and dynamic isoelectric focusing techniques, used to carry out two-dimensio ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  6. Respiratory Function Measurement System

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD07112

    To address the CBD need for a real-time measurement system for nonhuman primate tidal volumes, suitable for a Class 3 biological safety (BSL-3) cabinet, Physical Optics Corporation (POC) proposes to develop a new Respiratory Function Measurement (RFM) system. This system is based on a piezoelectric strain transducer that responds to movement of an animal’s thoracic cage during respiration. The ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense
  7. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense
  8. Computer-Assisted Strain Construction And Development Engineering (CASCADE)

    SBC: GENOMATICA, INC.            Topic: CBD06107

    The recent advances of modern high-throughput genomic technologies have resulted in a large number of fully sequenced microbial organisms. The construction of these comprehensive metabolic models serves many purposes including encapsulating all the data and allowing for in silco experiments to be performed that can drive experimental work and aid in strain development and optimization. The creatio ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  9. Handheld Instrument for Nerve Agent Detection

    SBC: KUMETRIX, INC.            Topic: CBD06104

    Rapid detection and identification of chemical warfare nerve agents (CWNAs) are critical to the screening and subsequent treatment of exposed warfighters. Inhibition of cholinesterase activity is insufficient as a marker of exposure to CWNAs, in that it can give misleading results and does not distinguish CWNAs from commonly employed pesticides. This proposal presents a revolutionary field-porta ...

    SBIR Phase II 2007 Department of DefenseOffice for Chemical and Biological Defense
  10. Respiratory Function Measurement System for Nonhuman Primates

    SBC: PHYSICAL OPTICS CORPORATION            Topic: CBD07112

    To address the CBD need for a real-time measurement system for nonhuman primate and rabbit respiratory tidal volumes suitable for a Class 3 biological safety (BSL-3) cabinet, Physical Optics Corporation (POC) proposes to develop a new Respiratory Function Measurement (RFM) system. This system is based on a piezoelectric transducer that responds to pressure generated by the animal’s thoracic cag ...

    SBIR Phase I 2007 Department of DefenseOffice for Chemical and Biological Defense

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