Award Data

The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

A personal air ventilation system (PAVS) can dramatically improve the environment inside chemical/biological protective clothing, protecting the health and safety of soldiers and enabling peak physical/mental performance for long periods. However, existing air blowers that can produce the flow rate and pressure drop needed for a PAVS are too heavy, inefficient, and noisy for a man-portable system ...

The primary objective of this effort is to design and develop a database management system (DBMS) and enable the integrated interpretation of the vast amounts of genomic and proteomic data in proper biological context. This DBMS will enable the development of diagnostic assays for human exposure to specific biological threat agents using an existing suite of systems biology tools. The DBMS design ...

A personal air ventilation system (PAVS) has the potential to dramatically improve the environment inside chemical/biological protective clothing. However, existing air blowers that can produce the flow rate and pressure drop required for a PAVS are too heavy and inefficient for use in a man-portable system. We propose to develop an innovative blower that can provide the required flow rate and p ...

This SBIR Phase I project will develop an evidence-based approach to maximize learning for K-12 students and predict learning outcomes. We propose to analyze data at multiple levels, including individual and group assessment data, and characteristics of the student, teacher, principal, and school. Using this data, we will categorize performance levels, determine the strengths and weaknesses of t ...

This Phase I R&D project will determine the feasability and commercial potential of a Data Services System designed to support district and school efforts to meet NCLB standards related to equity, continuous improvement, and accountability. The design incorporates: 1) a Data Use Framework representing a cohesive, innovative, and research-based approach for effectively structuring multiple uses of ...

In this Phase II SBIR project for the Army CBD, Torch Technologies of Huntsville, AL, will develop and demonstrate a fully operational prototype of its Advanced Chemical Release Evaluation System for fusing measurements of the concentration of clouds resulting from chemical releases. The ability to evaluate the performance of a stand-off detector during development depends on the ability to accura ...