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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Dynamic Warfighter Avatars with Complete Articulated Anatomy

    SBC: CFD Research Corporation            Topic: DHA17003

    Complete human anatomy avatars have a broad future role in advanced training environments, providing, for example, medically correct immersive experiences, performance-related physiological modeling studies, and in simulations for the purpose of designing protective armor. USARIEM have created individualized avatars as 3-D tetrahedral Finite Element (FE) meshes with full labeled anatomy, fitted to ...

    SBIR Phase I 2017 Department of DefenseDefense Health Program
  2. Personalized Warrior Health Avatar

    SBC: CFD Research Corporation            Topic: DHP16001

    The confluence of genetics, mobile computing, wearable sensors and computational physiology has started the revolution in personalized medicine with huge civilian and military prospects to promote health and reduce costs. The goal of this project is to develop and demonstrate a Warfighter Health Avatar (WHA): a framework and physiology based modeling tools of a warfighter body to enable assessment ...

    SBIR Phase II 2017 Department of DefenseDefense Health Program
  3. Portable Iron Screening System for Point-of-Care Iron Status Determination

    SBC: CFD Research Corporation            Topic: DHP16005

    Iron deficiency is one of the most common nutritional deficiencies in the United States. Left untreated, iron stores continue to deplete, resulting in iron deficiency anemia (IDA). Women undergoing basic military training are particularly susceptible to reduced and depleted iron stores. To-date, there are no point-of-care (POC) instruments for comprehensive, accurate determination of iron status. ...

    SBIR Phase II 2017 Department of DefenseDefense Health Program
  4. A Human Body Model for Computational Assessment of Blast Injury and Protection

    SBC: CFD Research Corporation            Topic: DHP13010

    There is a great need to establish an integrated framework for comprehensive analysis of blast injury events, evaluation of protective equipment and assessment of injury probabilities. Presently, such tool does not exist. The initial Phase II project has developed, partially validated and demonstrated a multiscale simulation framework integrating several blast injury biomechanics modeling componen ...

    SBIR Phase II 2017 Department of DefenseDefense Health Program
  5. Producing Novel Biosynthetic Therapeutics from Extreme Microbiomes

    SBC: IXPRESSGENES, INC.            Topic: CBD152004

    This project is a unique metagenomic evaluation of under-studied extremophilic microbiome natural products (NPs), with the goal of discovering novel antibiotic biowarfare agent (BWA) countermeasures. A metagenomic biosynthetic gene cluster library from extremophilic sources was created, sequenced, analyzed, and exploited to produce several broad-spectrum antibiotic extracts during the Phase I effo ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  6. Smartphone Application for Mask Sizing and Projecting Quantitative Fit

    SBC: CFD Research Corporation            Topic: CBD161005

    Typical procedures for respirator masks sizing and protective fit test are time-consuming and user intensive, requiring taking anthropometricmeasurements of the wearer, sampling the wearers breathing zone and the use of specialized tools and equipment. The proposed softwareapp aims to quickly, accurately and automatically perform respirator mask sizing and predict protective fit using only 2D imag ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  7. Exploiting Natural Products-Based Therapeutics for Aflatoxin Mitigation

    SBC: CFD Research Corporation            Topic: CBD152003

    Aflatoxins B1 (AFB1) are fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk for thedevelopment of hepatocellular carcinoma. Currently, there are no known countermeasures to selectively mitigate AFB1 toxicity. To meet thischallenge, we successfully validated a Phase I proof-of-concept study to harness the microbiome extracts of scavenging ma ...

    SBIR Phase II 2017 Department of DefenseOffice for Chemical and Biological Defense
  8. System for Prosthetic Alignment Utilizing Real-time Kinematics (spAUrk)

    SBC: Integrated Solutions For Systems, Inc.            Topic: DHA17008

    Major advances in prosthetic devices and aggressive rehabilitation over recent years have enabled many warfighters experiencing amputation to regain functional mobility, and often return to full active duty. A critical step to ensuring that these prosthetic devices function seamlessly with the patient is the initial alignment process. This alignment process is often iterative and time consuming, a ...

    SBIR Phase I 2017 Department of DefenseDefense Health Program
  9. Multiple Indication Adjuvants

    SBC: BIOPROTECTION SYSTEMS CORP.            Topic: CBD08105

    The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

    SBIR Phase I 2008 Department of DefenseOffice for Chemical and Biological Defense
  10. Development of a Database Management System to Enable Rapid, Efficient Assay Design for Use in Detection and Diagnosis of Human Exposure to Biological

    SBC: CFD Research Corporation            Topic: CBD07114

    Increases in amount and diversity of high-throughput data presents tremendous organizational and analysis challenges to researchers. Our objective in this effort is to address these challenges by designing and implementing a database management system (cipherDB) for the storage, management, analysis, and visualization of diverse biological data types. The Phase I design and implementation of ciphe ...

    SBIR Phase II 2008 Department of DefenseOffice for Chemical and Biological Defense

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