Award Data

This Small Business Technology Transfer (STTR) Phase I project shall utilize a multi-organizational team with uniquely experienced and multi-disciplinary personnel to demonstrate the feasibility of a new family of innovative sheet molding compounds (SMCs) that are partially bio-based and have lower density while having similar performance and cost. Kenaf natural fiber will be blended with glass fi ...

This Small Business Technology Transfer Research (STTR) Phase I project will employ a multi-component nanofiber spinning approach to develop a high-strength and high-modulus polymeric composite fiber, using the latest available islands-in-sea spinning technology and innovative spinning process parameters and polymer combinations. The goal of this project is to achieve a composite fiber wherein nan ...

Homologous recombination (HR) permits the precise insertion, deletion, or substitution of genetic material in the genome of an organism. HR offers numerous opportunities for modifying plant genomes to enhance our understanding of plant gene function and regulation, especially with respect to enhancing the production of biofuels. Although HR normally occurs at very low frequencies, approximately ...

We propose to use physiological sensors to measure the quality of a trainee's interaction with a virtual environment (VE) as a function of VE fidelity to enable design improvements in VEs and to enhance training effectiveness through feedback of physiological-based performance information. Currently, VE design is guided by subjective design models that involve multiple design iterations and focus ...

DESCRIPTION (provided by applicant): Newborn screening is currently performed by collecting dried bloodspots from infants and then sending them to a lab for analysis. There is an increasing necessity to screen for a number of disease conditions for which therapies are becoming available. Lysosomal storage diseases alone number greater than 40. There is a need to minimize the blood collecte ...

DESCRIPTION (provided by applicant): The great need for more efficient and effective oncologic drug development has driven the discovery and integration of biomarkers into all phases of clinical research. Further still, biomarkers are entering the clinical arena as early means of determining which patients are likely benefiting from a particular drug. One field of targeted therapy that has relied ...

DESCRIPTION (provided by applicant): Biomarkers of clinical activity are critical for targeted anti-cancer therapy development and are becoming important for the care of individual patients. In a prototypical tyrosine kinase pathway, governed by the epider mal growth factor receptor (EGFR), functional activity of the pathway is assessed by the phosphorylation status of EGFR and downstream signalin ...

Today’s Warfighter often carries an inordinate load that can lead to injuries and encumbered performance. Equipment is distributed among squad members with little, if any regard for differences in strength and anthropometry. Consequently, the current focus on human-centric design requires a modeling and simulation tool that can reduce the load Warfighters carry and can help distribute equipmen ...

In Phase I of the proposed program we plan to demonstrate the feasibility of manufacturing bladetrack components using an approach that will result in substantial reductions in cost and cycle time compared with conventional 2-D lay-up methods. The approach involves use of a 3-D fiber preform with the shape of the final component, produced by an orthogonal weaving process developed at 3TEX, which ...

The new material technology is based on 3D weaving for the reinforcement of buildings against both bomb blast and mitigation of the damage caused by flying objects. Four alternatives will be considered for the Phase I work dry 3D fabric, solid composite, sandwich core structures, and combination of these.