Award Data

This SBIR Phase I project will develop a web-based application that assists prospective and new college students in the challenging decision of the major/minor choice for their college degree. Studies have shown that 20 to 50 percent of students enter college as undecided in terms of intended majors, and subsequently an astonishing 75 percent actually change their major at least once before gradua ...

The broader impact/commercial potential of this project lies in the creation and test of a submersible micro mobile-sensor platform intended to measure fluid flow rates and precise temperatures inside shell-and-tube heat-exchangers. This research will empower follow-on capability for tube health and vibration measurement, creating the potential to save millions per employing facility by preventing ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) project is to improve the ability to amplify very long DNA in a few hours with high precision and few errors. The polymerase chain reaction amplification technology invented 30 years ago has revolutionized biomedical sciences. The proposed 100 kilobase (Kb) DNA amplification technology is ten times longer tha ...

The broader impact/commercial potential of this project is to enable vast deployment of energy storage to increase installation of renewable energy for reduced pollution and greenhouse gases, to improve energy security, and to improve energy efficiency and safety. The project will realize a dramatic reduction in cost and size of Energy Storage Systems (ESS) that will allow penetration of ESS into ...

This SBIR Phase I project will produce a Virtual Reality (VR)-based multiplayer game in which high school-aged players must collaboratively think through and solve complex, authentic Science-Technology-Engineering-Mathematics (STEM)-based problems. The United States faces a shortage of degreed STEM workers. More than half of high school students have indicated that they aren't pursuing STEM degree ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project is aimed at improving healthcare patient outcomes, potentially saving lives, and decreasing healthcare costs. The Drug Quality and Security Act of 2013 set stricter manufacturing standards on sterile injectable compounded medications that have closed many third party suppliers, thus creating s ...

Project Summary Abstract Behavioral parent trainingBPTis the gold standard treatment for disruptive behavior in preschool and elementary school age childrenDespite clear empirical evidence that it is effectiveadoption rates by practitioners remains woefully low due in part to a shortage of clinicians trained in BPTIn additioneven when BPT is administeredit is often done incorrectlyThe current stud ...

Project Summary Abstract Induced pluripotent stem cells iPSCs hold great promise in the areas of disease modeling and regenerative medicine and as a result have unique commercial potential There are currently more than ongoing clinical trials in stem cell therapies including the first in human trial using human iPSC derived retinal pigment epithelial cells to treat ...

Scarab Genomics goal is to commercialize carrier proteins for conjugate vaccine manufacture This proposal focuses on two bacterial carrier proteins that have been approved by the FDA and that are in use in pre clinical and clinical studies Exoprotein A EPA from Pseudomonas aeruginosa and Protein D PD from non typeable Haemophilus influenzae These proteins are difficult to make by the conve ...

Despite the tremendous success of short read next generation sequencingNGStechnologiestheir inherent inability to establish long range connectivity makes fundamental tasks such as genome closurehaplotype phasing and alternatively spliced transcript characterization all but impossibleNowtwo long read sequencing providersPacific BiosciencesPacBioand Oxford Nanopore TechnologiesONTare producing data ...