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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until April, 2020.

  1. Noninvasive Nocturnal Hypoglycemic Alarm

    SBC: ASL Analytical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A collaborative effort between ASL Analytical, Inc. and a research team at the University of Iowa is proposed to development a noninvasive nocturnal hypoglycemic alarm. The goal for the alarm system is to provide continuous noninvasive measurements during the sleep period of an individual with diabetes, sounding an audible alarm to wake the person if an impe ...

    STTR Phase I 2007 Department of Health and Human Services
  2. Profiling Cancer using Reverse-Phase NanoArrays

    SBC: BIOFORCE NANOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal describes a Phase I research study to test feasibility of using an ultra-miniaturized protein NanoArray for analysis of premalignant conversion and therapeutic monitoring in human cancer biopsy samples. B

    SBIR Phase I 2004 Department of Health and Human Services
  3. Biomolecular Profilometer

    SBC: BIOFORCE NANOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this SBIR Phase I feasibility study is to create a novel instrument called a BioProfilometer (BioPro) for label free detection of biomolecular interactions. The instrument measures the surface profile of a

    SBIR Phase I 2004 Department of Health and Human Services
  4. Development of a Humanized Pig Model of Cystic Fibrosis

    SBC: EXEMPLAR GENETICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene encodes a chloride channel that regulates ion flow across epithelial cell membranes. Most CF patients have a mutation that deletes phenylalanine 508 (?F508) and prevents CFTR from being properly processed and delivered to cell membr ...

    SBIR Phase I 2008 Department of Health and Human Services
  5. Energy Absorbing Transit Safe Wheelchair Caster

    SBC: FROGLEGS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): There are 1.7 million wheelchair users in the US. Many of these individuals use motor vehicles for transportation purposes. Due to the Americans with Disabilities Act (ADA) there is an increase of accessible i vehicles, allowing wheelchair occupants to stay seated in their wheelchair during transit. Unlike OEM motor vehicle seats, wheelchairs are not designed ...

    STTR Phase I 2004 Department of Health and Human Services
  6. BIODEGRADABLE MAGNESIUM STENTS WITH FINE MICROSTRUCTURE

    SBC: INDIVIDUAL AWARD--SHECHTMAN, DAN            Topic: N/A

    N/A

    SBIR Phase I 2007 Department of Health and Human Services
  7. Predicting stability of nucleic acid duplexes containing chemical modifications

    SBC: INTEGRATED DNA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Synthetic DNA and RNA oligomers are important tools for biological and medical assays including polymerase chain reactions, sequencing, DNA microarrays, antisense technology and RNA interference. Oligomers are generally used in experiments where they anneal to complementary sequences. Accurate predictions of annealing processes and duplex stability are therefor ...

    SBIR Phase I 2007 Department of Health and Human Services
  8. Gene Silencing with U1 Adaptor Oligonucleotides

    SBC: INTEGRATED DNA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our understanding of complex biological phenomena and disease progression has led to the realization that changes in the expression of genes underlie many of these processes. Developing reagents that can selectively al ter the expression level of any desired gene has been a goal of both scientists and clinicians for years. Historically, the most common approac ...

    SBIR Phase I 2008 Department of Health and Human Services
  9. Integrated oxygen/organic light-emitting device sensors

    SBC: Integrated Sensor Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The market for oxygen sensors is extremely large and continues to grow. Millions of medical patients in the U.S. alone require oxygen monitoring every year. Unfortunately, the current oxygen monitoring technology su

    SBIR Phase I 2004 Department of Health and Human Services
  10. Nutritional Intervention for Older Adult Muscle Loss

    SBC: MTI Biotech Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): Age-related muscle loss is a major public health issue affecting over 30 million Americans, with no viable treatments available to stem about an 8% loss in muscle mass every decade. Preliminary studies with beta-hy

    SBIR Phase II 2004 Department of Health and Human Services

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