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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. SBIR PHASE I RADIONUCLIDE THERAPY FOR METASTATIC MELANOMA VIEWPOINT MOLECULAR TARGETING LLC IGF OT IGF

    SBC: VIEWPOINT MOLECULAR TARGETING, INC.            Topic: NCI

    Not Available

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Detecting Ebola Virus Infections

    SBC: Aptalogic, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Ebolavirus attacks are devastating and unpredictable To control an ebolavirus outbreak it is essential to identify isolate and treat infected individuas rapidly However the available diagnostics ELISA and RT PCR require laboratory sophistication that is not possible at point of care in many African and other isolated locations Thus a portable device th ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Image guided therapy for metastatic melanoma

    SBC: VIEWPOINT MOLECULAR TARGETING, INC.            Topic: 102

    DESCRIPTION provided by applicant Melanoma incidence is growing faster than any other cancer and the American Cancer Society reports that death rates for melanoma have been rising in the United States for the past years Alarmingly melanoma is the most common cancer in young adults under One characteristic of metastatic melanoma cells that is recognized as a potential target for new the ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  4. The Brain Garden Serious Game: genetics, environment, behaviors and the brain

    SBC: Digital Artefacts LLC            Topic: 999

    DESCRIPTION provided by applicant As the average lifespan increases staying mentally sharp into old age is becoming a major concern for millions of individuals Neuroscience has developed a deep understanding of the factors influencing life long brain health with both genetic and lifestyle factors playing a large role how our brains age For example cardiovascular health education eating h ...

    SBIR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Early diagnosis of acute kidney injury by aptasensors

    SBC: Aptalogic, Inc.            Topic: 400

    DESCRIPTION provided by applicant Acute kidney injury AKI affects more than million people worldwide each year with reported mortalities from to in different patient populations However methods are lacking to support the early diagnosis of AKI that could lead to early intervention improved therapy better prognosis and lower medical costs For these reasons the development of e ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Humanized Pig Model of Cystic Fibrosis

    SBC: EXEMPLAR GENETICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene encodes a chloride channel that regulates ion flow across epithelial cell membranes. Most CF patients have a mutation that deletes phenylalanine 508 (?F508) and prevents CFTR from being properly processed and delivered to cell membr ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Gene Silencing with U1 Adaptor Oligonucleotides

    SBC: INTEGRATED DNA TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Our understanding of complex biological phenomena and disease progression has led to the realization that changes in the expression of genes underlie many of these processes. Developing reagents that can selectively al ter the expression level of any desired gene has been a goal of both scientists and clinicians for years. Historically, the most common approac ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Improved influenza A virus vaccines using alpha-Gal epitope modification

    SBC: NEWLINK GENETICS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Humans develop natural antibodies against a sugar molecule called Gal, which is present on proteins and lipids in most other species. These antibodies represent one of the strongest natural barriers to infection with ba cteria, parasites and viruses. NewLink Genetics has licensed this technology as the HyperAcute(c) vaccine and it is in Phase I and II clinical ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Novel Neuroprotective Agents for Parkinson?s Disease

    SBC: PK Biosciences Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by progressive and substantial loss of dopaminergic neurons in the substantia nigra compacta (SNc), resulting in severe neurological si gns including tremors, bradykinesia, and rigidity. The existing approaches to PD treatment are mainly focused on alleviating the motor symptoms ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  10. Noninvasive Nocturnal Hypoglycemic Alarm

    SBC: ASL Analytical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A collaborative effort between ASL Analytical, Inc. and a research team at the University of Iowa is proposed to development a noninvasive nocturnal hypoglycemic alarm. The goal for the alarm system is to provide continuous noninvasive measurements during the sleep period of an individual with diabetes, sounding an audible alarm to wake the person if an impe ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
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