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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Hybrid System for Ultrasound Signal, Spectral, and Image Analyses to Enhance Meat Quality Evaluation in Food Animals

    SBC: BIOTRONICS, INC            Topic: N/A

    Determining meat quality attributes in food animals is essential for genetic selection, sorting, and marketing. Ultrasound techniques have the potential to benefit the swine industry for improvements in both quality and yield measures by non-destructive means. There is a need to continually improve percentage intramuscular fat estimation accuracy and reduced bias, especially before integration of ...

    SBIR Phase I 2008 Department of Agriculture
  2. Ambient Processing and Nutritional Assessment of Trypsin-Inhibitor-Null Soybean Products

    SBC: SCHILLINGER SEED INC            Topic: N/A

    Commercial soybeans require heat processing to deactivate anti-nutrition factors/enzymes. Schillinger Seed has developed a new soybean free of the key anti-nutrition Kunitz Tyrpsin Inhibitor (SKTI-Null). This new SKTI-Null) soybean presents the opportunity for ambient or cold processing of soybeans for use in food and feed. The elimination of heat processing eliminates the need of a signifcant amo ...

    SBIR Phase I 2008 Department of Agriculture
  3. Development of a Humanized Pig Model of Cystic Fibrosis

    SBC: EXEMPLAR GENETICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. The CFTR gene encodes a chloride channel that regulates ion flow across epithelial cell membranes. Most CF patients have a mutation that deletes phenylalanine 508 (?F508) and prevents CFTR from being properly processed and delivered to cell membr ...

    SBIR Phase I 2008 Department of Health and Human Services
  4. Gene Silencing with U1 Adaptor Oligonucleotides


    DESCRIPTION (provided by applicant): Our understanding of complex biological phenomena and disease progression has led to the realization that changes in the expression of genes underlie many of these processes. Developing reagents that can selectively al ter the expression level of any desired gene has been a goal of both scientists and clinicians for years. Historically, the most common approac ...

    SBIR Phase I 2008 Department of Health and Human Services
  5. Improved influenza A virus vaccines using alpha-Gal epitope modification


    DESCRIPTION (provided by applicant): Humans develop natural antibodies against a sugar molecule called Gal, which is present on proteins and lipids in most other species. These antibodies represent one of the strongest natural barriers to infection with ba cteria, parasites and viruses. NewLink Genetics has licensed this technology as the HyperAcute(c) vaccine and it is in Phase I and II clinical ...

    SBIR Phase I 2008 Department of Health and Human Services
  6. Development of Novel Neuroprotective Agents for Parkinson?s Disease

    SBC: PK Biosciences Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Parkinson's disease (PD) is a debilitating neurodegenerative disorder characterized by progressive and substantial loss of dopaminergic neurons in the substantia nigra compacta (SNc), resulting in severe neurological si gns including tremors, bradykinesia, and rigidity. The existing approaches to PD treatment are mainly focused on alleviating the motor symptoms ...

    SBIR Phase I 2008 Department of Health and Human Services
  7. Computational Wind Tunnel: A Design Tool for Rotorcraft

    SBC: Sukra Helitek Inc.            Topic: A210

    Rotorcraft engineers traditionally use the wind tunnel to evaluate and finalize designs. Insufficient correlation between wind tunnel results and flight tests, have been often attributed in part to uncertainty in blockage corrections. Estimation of rotor blockage is significantly more complex than bluff body blockage as the correction depends on operational characteristics such as rotor RPM and ...

    SBIR Phase I 2008 National Aeronautics and Space Administration
  8. SBIR Phase I: Use of Dynamic Electric Field Gradients for the Crystallization of Proteins

    SBC: BioCrystals, LLC            Topic: BT

    This Small Business Innovation Research Phase I project is for the development of technology to crystallize proteins using less sample and with higher speed and success than current high throughput protein crystallization methods. Protein crystallization is an intermediate step in determining the precise three-dimensional shape of a protein, and proteins are involved in virtually every cellular pr ...

    SBIR Phase I 2008 National Science Foundation
  9. STTR Phase I:Video Analysis Techniques for Computer-Aided Quality Control for Colonoscopy

    SBC: EndoMetric, LLC            Topic: BT

    This Small Business Technology Transfer Phase I project will develop algorithms for a quality control system for colonoscopy (a procedure where the mucosa of the large bowel is inspected via a flexible tube with a camera on it) that has contributed to a marked decline in the number of colorectal cancer related deaths. However, recent data suggest that there is a significant miss-rate for the detec ...

    STTR Phase I 2008 National Science Foundation
  10. SBIR Phase I: Reducing Diesel Fuel Consumption in Recovering Woody Biomass

    SBC: Fleenor Manufacturing Inc.            Topic: EO

    This Small Business Innovation Research Phase 1 project develops a technology by which diesel fuel consumption can be significantly reduced while increasing productivity in recovering woody biomass. Diesel fuel is the number one operating cost of an industrial grinder and it is estimated that the diesel fuel consumed in processing the millions of tons of woody wastes each year in the United States ...

    SBIR Phase I 2008 National Science Foundation

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