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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. SBIR Phase I: Intelligent Drone Ignitions To Manage Fires

    SBC: Drone Amplified, Inc.            Topic: EW

    The broader impact/commercial potential of this project is the development of drone-based technology to manage fires more safely, efficiently, and effectively. Wildfires cause hundreds of billions of dollars in annual damages in the United States. As the size and number of wildfires increases, prescribed fires have emerged as one of the most cost-effective tools to reduce catastrophic damage by re ...

    SBIR Phase I 2019 National Science Foundation
  2. Multifunctional Antioxidant to Prevent Noise-Induced Hearing Loss

    SBC: Therapeutic Vision, Inc.            Topic: NIDCD

    Noise induced hearing lossNIHLis the most common occupational disease for which no clinically effective drug is availableSince NIHL involves oxidation linked loss of sensory hair cells and auditory neurons in the cochleathere is a need for potent and effective antioxidants that offer protection to these tissuesIn preliminary studies we have observed that the orally administered multifunctional ant ...

    SBIR Phase I 2018 Department of Health and Human Services
  3. Seromic Mucin Signature for the Early Diagnosis of Pancreatic Cancer

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 102

    ABSTRACT Pancreatic cancerPCis an extremely aggressive malignancy with one of the worst prognoses of all cancersWith marked resistance to chemoand radiotherapiessurgery is the only curative optionIn patients with localized diseasecomplete surgical resection provides five year survival rate ofHoweverandgtof patients are diagnosed with unresectable primary tumors and or distant metastasisThe major c ...

    SBIR Phase I 2018 Department of Health and Human Services
  4. MUC4/16 assay for the early diagnosis and management of benign and malignant pancreatic diseases

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 300

    Abstract The goal of this Fast track application is to develop a non invasive diagnostic testbased on MUCand MUCmucinsthat can serve as an adjunct to cytological analysis of fine needle aspiratesFNAsfor accurate prediction of malignancy in patients with cystic pancreatic lesionsDue to asymptomatic nature and lack of methods for early detectionrtof pancreatic cancerPCpatients present with an unrese ...

    SBIR Phase II 2018 Department of Health and Human Services
  5. Seromic Mucin Signature for the Early Diagnosis of Pancreatic Cancer

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: 102

    ABSTRACT Pancreatic cancerPCis an extremely aggressive malignancy with one of the worst prognoses of all cancersWith marked resistance to chemoand radiotherapiessurgery is the only curative optionIn patients with localized diseasecomplete surgical resection provides five year survival rate ofHoweverrtof patients are diagnosed with unresectable primary tumors and or distant metastasisThe major caus ...

    SBIR Phase II 2018 Department of Health and Human Services
  6. Rapid mRNA Expression Analysis by Quantitative Electrochemical Microarray at Sub-Zeptomole Levels without PCR and Labels

    SBC: VAJRA INSTRUMENTS, INC.            Topic: NHGRI

    Methods for obtaining transcriptome data have revolutionized our understanding of biological processes and disease dynamics at the fundamental levelimpacting health care on all three frontsdiagnosticsprognosticsand therapeuticsThe compiling of transcriptome informationat one end of the spectrum leads to discovery of genes and mutations usingfor examplethe Sanger method and NetGen sequencingand at ...

    SBIR Phase I 2018 Department of Health and Human Services
  7. A Prognostic Blood Test to Monitor Pancreatic Cancer Treatment by MiRNA Profiling

    SBC: VAJRA INSTRUMENTS, INC.            Topic: NCI

    Pancreatic ductal adenocarcinomaPDAChas ayear survival rate of less thanThe success in developing therapies for other cancers over the last two decades has not improved the dismal overall survivalOSrate for PDACIt is now becoming increasingly apparent that personalized medicine based on the genetics of a tumor will be essential for developing a treatment strategyThusthere is an urgent need to deve ...

    SBIR Phase II 2018 Department of Health and Human Services
  8. Fuel Efficiency Improvements for Amphibious Vehicles

    SBC: PACIFIC ENGINEERING INC.            Topic: N162079

    This Phase II project goal is to develop solutions that improve the fuel efficiency of Amphibious Vehicles. Amphibious vehicles operate on the leading edge of an assault and in environments where ongoing access to fuel is limited. More efficient fuel usage will also enable longer mission durations and increased operating ranges. The goal is to reduce fuel usage over the Amphibious Vehicle mission ...

    SBIR Phase II 2018 Department of DefenseNavy
  9. SBIR Phase II: Novel Device for Maintaining Continuous Fluid Drainage in Small-Bore Chest Tubes after Cardiothoracic Surgery

    SBC: Esculon LLC            Topic: BM

    The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project is to significantly improve outcomes for cardiothoracic surgical patients while reducing healthcare costs by ensuring proper post-surgical drainage. In the United States, approximately 750,000 major cardiothoracic surgeries are performed each year. Each of these patients receives an average o ...

    SBIR Phase II 2017 National Science Foundation
  10. Next Generation Western for high-throughput and high-content protein analysis

    SBC: LI-COR, Inc.            Topic: 100

    Abstract The identification and quantification of specific proteins in complex samples are critical processes in discoveringunderstandingand ultimately addressingthe underlying nature of human health and diseaseThe western blot is a fundamental method used for these processes due to the sensitivity and specificity enabled by combining protein sizing with immuno detectionDespite being widelyusedthe ...

    SBIR Phase II 2017 Department of Health and Human Services

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