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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. Patient-specific therapy of glioblastoma using lightly-labeled [14C]-temozolomide

    SBC: ACCIUM BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): It is widely accepted that the existing clinical paradigm of one treatment fits all is a major factor in the lack of progress in the effective treatment of a highly heterogeneous diseases. We propose a new innovative cl inical paradigm that optimizes brain cancer therapy using patient-specific markers of therapeutic response. Our long-term objective is to impro ...

    SBIR Phase I 2008 Department of Health and Human Services
  2. All-Fiber Components for Micro-Structured Fibers

    SBC: Aculight Corporation            Topic: S101

    We propose new concepts for developing components for high performance space based Lidar systems. While it is generally recognized that photonic crystal fiber technology can extend the performance range of fiber laser based sources these fibers are considered by many to be incompatible with complementary component technology such as fused couplers and pump combiners. Integration of these fibers i ...

    SBIR Phase I 2008 National Aeronautics and Space Administration
  3. Fiber-based, high-energy, ultra-short pulse eye-safe source

    SBC: Aculight Corporation            Topic: N08050

    Tactical laser sources delivering high-peak-power (from multi-MW to TW) in agile optical pulse trains at high pulse repetition frequency (PRF) in the eye-safe wavelength region are of interest for several military applications including proactive infrared countermeasures (PIRCM), non-lethal munitions, and remote sensing of battlefield threats. To meet the needs for future tactical lasers, Aculigh ...

    SBIR Phase I 2008 Department of DefenseNavy
  4. High Power IR/UV Laser for Accelerator Systems

    SBC: Aculight Corporation            Topic: 03d

    Electron accelerators allow researchers to advance energy and luminosity frontiers and expand our knowledge of nuclear physics and basic materials science. To achieve the best performance, specialized lasers are used to produce electrons for these accelerators. The lasers not only must be precise and reliable but also much more powerful than those that are currently available. This project will de ...

    SBIR Phase I 2008 Department of Energy
  5. Fiber-based, high peak power mid-infrared source

    SBC: Aculight Corporation            Topic: AF071005

    Tactical laser sources delivering high peak power (from multi-MW to TW) in agile optical pulse trains at high pulse repetition frequency (PRF) in the 3.5-4 µm wavelength region are of interest for several military applications including proactive infrared countermeasures (PIRCM), non-lethal munitions, and remote sensing of battlefield threats. To meet the needs for future tactical lasers, Aculig ...

    SBIR Phase II 2008 Department of DefenseAir Force
  6. Optical nerve stimulation for a vestibular prosthesis

    SBC: Aculight Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Vestibular disorders represent a debilitating medical problem by causing balance and vision impairments that adversely affects the lives of people of all ages and backgrounds. The restoration of vestibular function by d irect stimulation of the vestibular nerve, bypassing the sensory organs, is expected to alleviate these symptoms in some patients. Currently, t ...

    SBIR Phase I 2008 Department of Health and Human Services
  7. IMPROVED DIAGNOSTIC INFRARED NERVE STIMULATOR FOR ENT NERVE MONITORING

    SBC: Aculight Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Iatrogenic nerve damage is one of the most adverse sequalae of tumor resection surgery in all parts of the body. Many neuromonitoring techniques have been developed to lower the incidence of damage, most notably electr ostimulation. However, the clinical potential of precise neuromonitoring remains unfulfilled, due to several key limitations intrinsic to elect ...

    SBIR Phase I 2008 Department of Health and Human Services
  8. Improved Efficiency Fiber Laser Modules for Beam Combining

    SBC: Aculight Corporation            Topic: MDA04005

    SBC of high-power fiber lasers uniquely links an efficient, versatile, and robust power scaling architecture to individual emitters with outstanding efficiency, diffraction-limited beam quality, and distributed thermal loading. Fiber SBC, thus provides an exceptionally promising pathway to scalable, high efficiency laser systems with high average power, superb power-to-mass ratios, and near perfec ...

    SBIR Phase II 2008 Department of DefenseNavy
  9. Peptide-Modified Sulfonated Styrene Block Copolymers for Vascular Applications

    SBC: AEGIS BIOSCIENCES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): A novel sulfonated polymer with unique chemically tailorable properties and processing characteristics has shown considerable promise as a thrombo- resistant surface and has been proven to be effective inhibitor against neutrophil- derived proteases. A phase 1 SBIR testing is proposed to investigate this polymer as a tailorable interface coating for blood-cont ...

    SBIR Phase I 2008 Department of Health and Human Services
  10. Low-Stored-Volume Wings for a Very High Altitude Aircraft

    SBC: ANDREWS SPACE, INC.            Topic: SB072042

    Andrews Space proposes an inflatable rigidizable wing that can be stored folded or rolled up, and deployed at altitude via an inflation system, and will then cure to form a rigid wing improving the reliability and reducing the risk of an inflatable wing. It will also be much lighter and have a much smaller storage volume than a mechanically folding wing. A high altitude, long endurance aircraft c ...

    SBIR Phase I 2008 Department of DefenseDefense Advanced Research Projects Agency

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