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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 1 - 10 of 6024 results
  1. Randomized Prospective Phase II Clinical Trial of NVX-108 in Association with Chemoradiation of Glioblastoma

    SBC: NUVOX PHARMA, L.L.C.            Topic: 102

    Glioblastoma multiforme (GBM) is a malignant primary brain tumor affecting about 12,000 new cases per year in the U.S. Average survival is only about 14-15 months. Radiation (RT) is most commonly administered as 30 fractions of 2 Gray each over 6-weeks with concomitant temozolomide (TMZ). GBM tumors are hypoxic. The primary mechanism of RT is creation of singlet oxygen; hypoxia within GBM adversel ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  2. Clinical Evaluation of a Resorbable Vena Cava Filter

    SBC: Adient Medical Inc.            Topic: NHLBI

    PROJECT SUMMARYClinical Evaluation of a Resorbable Inferior Vena Cava FilterPulmonary embolismPEis therd leading cause of deathclaiming the lives of at leastAmericans annuallymore than breast cancerAIDSand vehicle fatalities combinedMetallic Inferior Vena CavaIVCfilters have been proven effective in reducing PE to aboutin at risk populationshoweverthey come with a heavy post deployment pricenamely ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Correlating TCR diversity to immune reconstitution after cord blood transplant

    SBC: ADAPTIVE BIOTECHNOLOGIES CORPORATION            Topic: NHLBI

    DESCRIPTION provided by applicant Many patients requiring stem cell transplantation for hematological malignancies are unable to find a suitable HLA matched sibling or unrelated donor Transplants using stem cells from umbilical cord blood provide an alternative for these patients allowing transplantation to proceed with less stringent HLA matching requirements Unfortunately in addition to t ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Unicondylar Resurfacing in an Ovine Osteoarthritis Disease Model

    SBC: Cytex Therapeutics, Inc.            Topic: NIAMS

    AbstractThe treatment of large cartilage lesions is a difficult clinical problem for which there are few good solutionsLeft untreatedthese lesions tend to degenerate to chronic pain and osteoarthritisOAultimately requiring a total joint replacementFor patients suffering from knee OAandin particularunicompartmental OAunicondylar knee arthroplastyUKAis an available first line treatment option that p ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. An Integrated Microarray Printing and Detection System

    SBC: BIOSENSING INSTRUMENT INC            Topic: 400

    DESCRIPTIONprovided by applicantMicroarray technology has dramatically advanced the study of protein interactions leading to discovery and validation of new biomarkers and therapeutic drugsTypicallyprotein microarrays are pre spotted with target molecules in one device and then tested with probe molecules using another deviceDuring each testing cyclethe entire microarray becomes exposed to the pro ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Service and Software Solution for the Rigorous Design of Animal Studies

    SBC: SERALOGIX, LLC            Topic: NIDA

    The primary goal of this fast track project is to commercialize a cloud based software suite complemented with on call expert services to guide life science researchersthat may have minimal statistical and experimental designEDknowledgeto rigorously planoptimizejustifymanageand report results for complex animal studiesInadequately planned experimentse glack of randomization blinding and diversityl ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  7. An Ultra filtrate perfusion bio artificial pancreas for high-density islet replacement without immunosuppression

    SBC: Cell-Safe Life Sciences LLC            Topic: NIDDK

    DESCRIPTIONprovided by applicantThe Cell SafeTM is a fundamentally new approach in replacement of dysfunctional insulin producing cells in patients with diabetesby transplantation of new islets in a three dimensional scaffold embedded in a highly compatible bioengineered perfusion system that continuously supplies tissue fluidblood ultrafiltrateso that the cells ae protected from immune rejection ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  8. STTR Phase I: Autonomous Landing of sUAS onto Moving Platforms

    SBC: PLANCK AEROSYSTEMS INC.            Topic: EW

    The broader impact/commercial potential of this project is the expansion of autonomous unmanned aerial systems (UAS, or drones) to new maritime operational environments and commercial markets. The proposed technology will enable small UAS to operate from vessels moving at sea, without the need for a dedicated pilot or installed hardware, even while far from shore and beyond the reach of establishe ...

    STTR Phase I 2017 National Science Foundation
  9. STTR Phase I: A Low Cost Robotics kit for Elementary Education

    SBC: BirdBrain Technologies LLC            Topic: EA

    This project intends to design and develop a programmable electronics and robotics kit that catalyzes the learning of computational thinking, engineering design, and making at a price point that will be affordable for large numbers of elementary school classrooms throughout the nation. Such an educational robotics kit benefits society by positively influencing science, technology, engineering, and ...

    STTR Phase I 2017 National Science Foundation
  10. STTR Phase I: Hydrogen Storage in Catalytically-modified Porous Silicon

    SBC: GREEN FORTRESS ENGINEERING, INC.            Topic: CT

    This STTR Phase I project will study the storage of hydrogen on a novel material produced from silicon - the same substance used to make solar panels and computer chips. This unique and patented approach has the potential to eclipse all prior methods of hydrogen storage in terms of pressure, temperature, safety, cost, and convenience. Silicon is earth-abundant and benign to humans - it is even pro ...

    STTR Phase I 2017 National Science Foundation
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