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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

Displaying 1 - 10 of 5974 results
  1. Topic 368: Biotherapy of Brain Tumors by Radioiodinated SapC-DOPS Nanovesicles

    SBC: Molecular Targeting Technologies, Inc.            Topic: NCI

    There is an urgent need for more effective drug delivery agents for treatment of brain tumors, which are among the most aggressive and intractable cancers. SapC-DOPS, a nanovesicle composed of saposin C (SapC) coupled to dioleoylphosphatidylserine (DOPS), has proven tumor targeting properties, which include crossing the blood-brain tumor barrier and binding the lipid tumor marker, extracellular ph ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. TOPIC 363: myCare2- Supporting Caregivers and Caregiving

    SBC: BRIGHTOUTCOME INC.            Topic: NCI

    The myCare2 solution will be marketed to cancer care organizations and include three separate portals for cancer caregivers, patients and providers. The system will be mobile-enabled and support standards-based EHR integration. Primary myCare2 features include symptom assessment, communication with the care team, care plan dissemination, tailored education content for caregiving and for caregiver ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Topic 364: SysMet: Integrative Systems Metabolomics

    SBC: OmicsCraft LLC            Topic: NCI

    Metabolomics plays an indispensable role in the growing systems biology approaches to identify reliable cancer biomarkers. Liquid chromatography coupled to mass spectrometry (LC-MS) and gas chromatography coupled to mass spectrometry (GC-MS) have been extensively used for high-throughput comparison of the levels of thousands of metabolites among biological samples. However, the potential values of ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. TOPIC 360: A SIMPLE END-TO-END SYSTEM FOR SERIAL CELL SORTING AND MANIPULATION USING A SINGLE CONTAINER

    SBC: DIAGNOLOGIX, LLC            Topic: NCI

    Chemotherapy may control but rarely cure metastatic cancers. Remarkably, modern immunotherapies, including cell-based therapies, have cured metastatic melanomas and other types of cancers. A major challenge for all cell therapies in general is the need to develop cost-effective and efficient manufacturing and delivery capabilities. We have recently established an innovative cell isolation technolo ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. TOPIC 356: FLOUROGENIC ASSAY PLATFORM FOR CIRCULAR RNA DETECTION

    SBC: Lucerna Inc.            Topic: NCI

    Circular RNAs (circRNAs) are a novel class of non-coding RNAs that are an abundant component of the epitranscriptome. Putative functions of circRNAs, include miRNA sequestration, RNA-binding protein scaffolding, mRNA trapping, and protein translation regulation. Deregulation in one or more of these roles has been linked to several types of cancer, including pancreatic cancer, basal cell carcinoma, ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Phosphorus biofertilizer for sustainable crop production

    SBC: Biomineral Systems LLC            Topic: 812

    The proposed project pertains to the development of a novel phosphorus biofertilizercomprising special seeds and seed treatments to reduce the need for P fertilizers in cropproduction by up to 50%. Our biofertilizer is therefore an environmentally sustainable, and costeffectiveamendment to synthetic and organic phosphorus fertilizers. Sustainable production offood and energy crops is critical beca ...

    SBIR Phase I 2018 Department of Agriculture
  7. On-Farm Conversion of Solar Energy, Water, and Carbon Dioxide to Hydrocarbon Fuel

    SBC: Giner, Inc.            Topic: 812

    Fossil fuels are the dominant energy source in the agriculture sector, comprising a large fraction of farming operational expenditures and emitting CO2 as a greenhouse gas. Despite recent market penetration, renewable energy adoption on farms remains low. Large capital costs, intermittency, and immobility of renewable energy prevents adoption on small and mid-size farms. A particularly detrimental ...

    SBIR Phase I 2018 Department of Agriculture
  8. Evaluating the Feasibility of Cultivating Yaupon Holly for its Food Value

    SBC: YAUPON Wellness Company, Inc            Topic: 812

    Project Summary/AbstractWith over a trillion cups of caffeinated beverages consumed each year, caffeine is arguably the world's most frequently consumed stimulant. Caffeine is widely used to enhance athletic performance, body composition, pain relief, and mental acuity. Naturally caffeinated beverages include coffee, black and green tea, cola, cocoa, guarana, yerba maté, and Yaupon tea. ...

    SBIR Phase I 2018 Department of Agriculture
  9. Small and Mid-size Farm Efficiency Ecosystem

    SBC: Boston Labs Design and Development LLC            Topic: 812

    Small farms are critical to the futureof America. Small farms promote and sustain communities, create jobs, improve the health of the land and of the people who live on it. Currently small to mid-sized farms raising pasture-based livestock have been left to invent/build their own feeding/watering systemsand are at a disadvantage to large, fully automated, high-efficiency systems on large scale far ...

    SBIR Phase I 2018 Department of Agriculture
  10. Development of a Small-Scale HTST Milk Processing Line for Small and Mid-Size Dairy Farms

    SBC: Atlantic Corporation            Topic: 812

    Project Description and Objectives:The overarching goal of this SBIR project is to develop a cost-effective, small-scale milk processing line for HTST pasteurization as a pathway to increased revenue and profitability for small and mid-size dairy farms. Intensive research will answer critical questions in two key areas: 1) Technical Feasibility - analysis of currently available processing line com ...

    SBIR Phase I 2018 Department of Agriculture

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