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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Clinical Testing of an Insulin Analog

    SBC: THERMALIN DIABETES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The central goal of insulin replacement therapy in the treatment of Type 1 diabetes mellitus (T1DM) is tight control of blood glucose concentration. This Phase I STTR application, submitted by Thermalin Diabetes, Inc., in conjunction with Case Western Reserve University, seeks support for the pre-clinical testing and commercial development of an ultra-stable a ...

    STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Measurement and classification of vertical and shear forces and distributions in

    SBC: BERTEC CORP            Topic: N/A

    DESCRIPTION (provided by applicant): Foot ulcers are a prevalent complication in the diabetic population, and despite that, the exact causation of plantar ulcers is still unknown. Research suggests that vertical pressure and horizontal shear play an integral role, but the pressure and shear distributions must be precisely measured on the entire plantar surface. Unfortunately, only pressure distrib ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Imaging in Developmental Toxicology

    SBC: BIOINVISION INC            Topic: N/A

    DESCRIPTION (provided by applicant): Cryo-imaging, as developed by BioInVision, Inc., and fluorescent reporter gene transgenic mice will be used to determine even subtle or rare developmental abnormalities resulting from toxic exposures. By alternately sec- tioning and imaging, the cryo-imaging system will acquire 3D, high-resolution anatomical color and cellular fluorescence images. The cryo-imag ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  4. A Device to Reduce Anastomotic Failure in the Treatment of Colorectal Cancer

    SBC: SURGISENSE CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Anastomotic failure is one of the most feared complications of gastrointestinal surgery due to the resultant morbidity and mortality. Failure of an anastomosis, or intestinal junction, can cause a spectrum of morbidities to the patient including local abscess formation - requiring procedural drainage, tumor recurrence, debilitating pain, dysfunctional defecatio ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  5. Model 8686H, Precision Resistance-Ratio Bridge

    SBC: Circuit Equipment Corporation            Topic: N/A

    The result of this project will be a fully functional prototype of the Model 8686H Precision Resistance-Ratio AC Bridge. The unit is capable of measuring resistances from 0 to 400 ohms with better than 0.1 uohm resolution and an accuracy of better than +/-0.05ppm. The unit will have advanced features such as a built-in web-browser, USB interface and built-in complex functions. Examples of such com ...

    SBIR Phase II 2009 Department of CommerceNational Institute of Standards and Technology
  6. Expressive Integrity Constraint Validation with OWL

    SBC: Clark & Parsia, LLC            Topic: N/A

    We propose to develop a commercially adequate, robust and perfomant OWL-based Integrity Constraint (IC) validation system with several innovations, including novel debugging and explanation support for data integrity errors; incremental and optimized validation of data integrity; and a unified system for validating structured, semi-structured, and semantic data. A rigorous and formal specification ...

    SBIR Phase II 2009 Department of CommerceNational Institute of Standards and Technology
  7. Nighttime Acoustic Pharyngometer (NAP) for Airway Obstruction Identification

    SBC: CLEVELAND MEDICAL DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The ability to define the location of airway obstructions in Obstructive Sleep Apnea (OSA) patients is critical for surgical and oral appliance treatments because these therapies target the manipulation or removal of specific collapsible oropharyngeal regions. Yet, to this date, there are no adequate tools that can accurately and conveniently locate the collaps ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  8. ParkinStep: Automated PD Gait and Balance Assessment for Optimizing DBS

    SBC: CLEVELAND MEDICAL DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective is to design, build, and clinically assess ParkinStep , a compact, portable, wireless movement disorder monitor technology to quantify gait and balance performance in Parkinson's disease (PD). A standardized platform for repeatable, automated testing to assess gait and balance in response to deep brain stimulation (DBS) settings should optimize p ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  9. BradyXplore: Bradykinesia Feature Extraction System

    SBC: CLEVELAND MEDICAL DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective is to design, implement, and clinically assess a portable, user worn, bradykinesia feature extraction system, BradyXplore , for easy integration with CleveMed's existing ParkinSense technology platform. Idiopathic Parkinson's disease (PD) and other parkinsonian disorders affect millions of people. Three major symptoms responsible for functional d ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Stimulation Induced Modulation of Sleep

    SBC: CLEVELAND MEDICAL DEVICES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The peripheral chemoreceptors (carotid primarily, and the aortic bodies) detect changes in arterial blood oxygen and carbon dioxide, and initiate reflexes that are important for maintaining homeostasis during hypoxemia. The response to changing carbon dioxide (CO2) levels produces major changes in respiratory drive, of special importance to the control of venti ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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