Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Electronic Image Trial Management System

    SBC: VIRTUALSCOPICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Delays in FDA drug approval are measured in lost lives (estimated to be hundreds of thousands over the last few decades) and increased costs to U.S. citizens for drugs that are eventually approved. One factor contributing to the delay in drug approvals is the widespread use of time-consuming and error-prone manual methods to deliver medical images (i.e. CT, MR, ...

    STTR Phase I 2009 Department of Health and Human Services
  2. Cardiac Regenerative Therapy with Cyclin A2

    SBC: VentriNova, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The morbidity and mortality due to cardiovascular disease is attributed to the lack of significant replicative potential of adult mammalian cardiomyocytes. Thus myocyte loss in response to ischemic injury typically results in scar formation and a decline of cardiac function that is usually irreversible. The cessation of myocyte proliferation is associated with ...

    STTR Phase I 2009 Department of Health and Human Services
  3. Vascular Targeting for Imaging and Treatment of Benign Prostatic Hyperplasia

    SBC: ANDROBIOSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Benign Prostatic Hyperplasia/Hypertrophy is a major health problem in the United States, with one-in-three men having urologic problems. Currently available treatment modalities include alpha-blockers that do not affect the underlying pathologic process, and 5-alpha-reductase inhibitors that have significant systemic side-effects. We have discovered that human ...

    SBIR Phase I 2009 Department of Health and Human Services
  4. Primary Xenografts of Human Tissue as Surrogates of Cancer In Situ

    SBC: ANDROBIOSYS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): AndroBioSys, Inc. is dedicated to the development of human tissue-based in vivo tools capable of selecting better targeted agents for clinical trials by improved preclinical testing. AndroBioSys has developed the technology for reproducible implantation of primary xenografts of benign and malignant human prostate and kidney tissue. Xenografts have been establis ...

    SBIR Phase I 2009 Department of Health and Human Services
  5. In Vitro Feasibility of a Rapid Response Continuous Glucose Sensor

    SBC: Ultradian Diagnostics, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Numerous research publications have demonstrated the benefits of continuous glucose monitoring for better glucose control and reduced glycated hemoglobin (HbA1c) levels; however, to improve efficacy, significant improvements in the performance of implanted glucose sensors are required. The proposed Phase 1 research is focused on developing a rapid, microsecond, ...

    SBIR Phase I 2009 Department of Health and Human Services
  6. Outbreak detection:combinatorial tests for small samples

    SBC: Applied Biomathematics Inc            Topic: N/A

    DESCRIPTION (provided by applicant): In delimited populations, such as nursing homes, day care centers, prisons, hospitals, and cruise ships, serious outbreaks of illness generally produce small absolute numbers of disease incidence. Moreover, these groups are often more susceptible to disease than the general population (e.g. Garibaldi et al. 1981, Nimri 1994, March et al. 2000). Additionally, th ...

    SBIR Phase II 2009 Department of Health and Human Services
  7. Super-Zoom Endoscope (SuZE)

    SBC: APPLIED SCIENCE INNOVATIONS, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Endoscopes used in urology for transurethral imaging and procedures have small diameters on the distal end for minimal invasiveness. The resolution of such endoscopes is relatively low. While larger, laparoscopic imaging tools now routinely offer high-definition image quality; the endoscopic images still typically contain nearly 100 times fewer pixels. Emerging ...

    SBIR Phase II 2009 Department of Health and Human Services
  8. The Creation of ASDRA (Autism Spectrum Disorder Risk Alert)

    SBC: Tiranoff Productions LLC/GeneticaLens            Topic: N/A

    DESCRIPTION (provided by applicant): GeneticaLens, a multi-media video production and technology services company, has joined forces with a team of leading researchers in the early detection of Autism Spectrum Disorders (ASD) to create the Autism Spectrum Disorders Risk Alert (ASDRA ). ASDRA is a software system and integrated web based toolset with access to a video-intensive database, that faci ...

    SBIR Phase II 2009 Department of Health and Human Services
  9. Intracavitary Hemostatic Agent for Non-compressible Hemorrhage

    SBC: BIOMEDICA MANAGEMENT CORP.            Topic: N/A

    DESCRIPTION (provided by applicant): Hemorrhage resulting from traumatic injuries is a major cause of death in accidents, and the primary cause of death on the battlefield. Over 40% of the trauma cases admitted at hospitals in the USA, are due to road traffic accidents. Hemorrhage is the primary cause of death on the battlefield in conventional warfare. The vast majority of these deaths occur befo ...

    SBIR Phase II 2009 Department of Health and Human Services
  10. Multi-antigen peptide assay for the serodiagnosis of Lyme disease

    SBC: Biopeptides, Corp            Topic: N/A

    DESCRIPTION (provided by applicant): Lyme Disease (LD) is the most common vector-borne infectious disease in the United States and remains a significant public health concern. The laboratory diagnosis of LD depends on the demonstration of antibodies against Borrelia burgdorferi. Current serologic assays are not specific enough and not sensitive in early LD. New assays are needed and we plan to fi ...

    SBIR Phase II 2009 Department of Health and Human Services
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