Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Real-time Adherence and Risk Management of Opioid Therapies

    SBC: MedicaSafe Inc            Topic: NIDA

    DESCRIPTION (provided by applicant): Following a highly successful Phase I award, this Phase II SBIR application proposes development of MedicaSafe Opioids - a risk management system for the treatment of chronic pain patients prescribed opioid therapies. The need for this system arises from the dramatic increase in the use of opiod painkillers. Although this form of medication can be highly effect ...

    SBIR Phase II 2012 Department of Health and Human Services
  2. Clinical System for Measurement of Oral Crest Height Change in Dental Radiographs

    SBC: Imagination Software Corporation            Topic: NIDCR

    DESCRIPTION (provided by applicant): Twenty-six percent of the population twenty years and over have destructive periodontal disease (gt 4 mm loss of bone height). Alveolar bone height correlates well with subsequent tooth loss. Moreover, it has been foundthat periodontal disease correlates with other diseases, e.g., atherosclerosis and diabetes. Proper diagnosis, treatment, maintenance, and patie ...

    SBIR Phase II 2012 Department of Health and Human Services
  3. Repair of Bone Defects with Human Autologous Pluripotent Very Small Embryonic lik

    SBC: Caladrius Biosciences            Topic: NIDCR

    DESCRIPTION (provided by applicant): Bone loss due to fractures and disease is a serious medical condition in the US affecting millions of Americans. It is particularly a problem with oral craniofacial disorders were the costs of treating damage exceeds60 billion annually. Furthermore, periodontitis is associated with systemic disorders such as diabetes mellitus, preterm low birth weight, and car ...

    SBIR Phase II 2012 Department of Health and Human Services
  4. Gene transfer to treat urinary urgency frequency nocturia and incontinence

    SBC: Ion Channel Innovations, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): This grant application is initiated by Ion Channel Innovations, LLC., (ICI) an early stage biotechnology company that has completed the first, and only, phase I safety trial using plasmid DNA transfer with a non-specific gene MaxiK potassium channel promoter to treat urinary urgency, frequency, nocturia, and incontinence also known as overactive bladder or OAB ...

    SBIR Phase II 2012 Department of Health and Human Services
  5. Photoactivated Antimicrobial Collagen

    SBC: CONVERSION ENERGY ENTERPRISES            Topic: NIGMS

    DESCRIPTION (provided by applicant): The significance of this project is the development of a novel photoactivated collagen dressing with demonstrated bactericidal effects, minimal toxic effects and low susceptibility to mechanisms of microbial resistancein an effort to ultimately expand the armamentarium of antimicrobial agents for the management of wound infections. Approximately 2 million patie ...

    SBIR Phase II 2012 Department of Health and Human Services
  6. Separate Fact from Fiction in Cases of Child Abuse: A Tool for Pediatricians

    SBC: L A Bruell, Inc.            Topic: NICHD

    DESCRIPTION (provided by applicant): Phase II of Stop, Look and Listen (SLL): Separating Fact from Fiction in Evaluating Cases of Child Abuse: an Interactive Learning Tool for Pediatricians seeks to improve the frequency of reporting and accuracy of childabuse assessment and reduce racial bias in reporting of suspected child abuse. The Phase II program will meet the following specific objectives: ...

    SBIR Phase II 2012 Department of Health and Human Services
  7. Clinical Development of Hemostatic Agent ClotFoam for Severe Hemorrhage

    SBC: BIOMEDICA MANAGEMENT CORP.            Topic: NHLBI

    DESCRIPTION (provided by applicant): ClotFoam(R) , is a novel adhesive sealant composition and second-generation hemostatic agent. This biological agent was designed to arrest moderate to severe blood loss arising from intracavitary traumatic injury orintraoperative hemorrhage without compression, stitches or staples. Control of Intraoperative hemorrhage in laparoscopic surgery-which is increas ...

    SBIR Phase II 2012 Department of Health and Human Services
  8. An inhaled PDGF receptor inhibitor for the treatment of pulmonary arterial hyper

    SBC: Pulmokine, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The purpose of this Phase II project is to develop a new treatment for pulmonary arterial hypertension (PAH) consisting of the inhaled platelet derived growth factor receptor (PDGFR) inhibitor PK10453. PAH is a diseaseof the pulmonary vasculature associated with high morbidity and mortality. Signaling through the PDGFR leads to smooth muscle cell proliferation ...

    SBIR Phase II 2012 Department of Health and Human Services
  9. Scalable Software for Reverse Engineering Neural Circuits from Histology

    SBC: Kitware, Inc.            Topic: NIMH

    DESCRIPTION (provided by applicant): A human brain is estimated to have roughly 100 billion neurons connected through more than 100 thousand miles of axons and a quadrillion of synaptic connections (~10 15 or 2 50 connections). As a comparison, there aremore synaptic connections in human brains in the city of Boston alone than grains of sand in all the desserts and beaches in the world (~10 20). ...

    SBIR Phase II 2012 Department of Health and Human Services
  10. A Culturally and Linguistically Specific Deaf Depression Screener

    SBC: SOCIAL SCIENCES INNOVATIONS CORPORATION            Topic: NCATS

    DESCRIPTION (provided by applicant): Hearing impairment/deafness is the most common sensory limitation in the U.S. An estimated 11 million individuals in the US are deaf or hard-of-hearing. It has been estimated that approximately 1 million Americans use American Sign Language (ASL) as their primary means of communication making it a distinct linguistic minority. This proposal seeks to improve cli ...

    SBIR Phase II 2012 Department of Health and Human Services
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