Award Data

ABSTRACT: Autonomous vehicles lack a standardized mechanism for seamless cross-platform sharing of testing frameworks and evaluations of basic tasks. The ability to execute common tests on various hardware platforms is essential in order to be able to e

DESCRIPTION provided by applicant The pre fusion conformation of the RSV F protein preF is the primary determinant of neutralization in immunized sera However this conformation is unstable and rapidly transitions to the postfusion conformation A disulfide stabilized prefusion variant with cavity filling mutations DS Cav has been shown to yield high neutralizing titers in animals howeve ...

DESCRIPTION provided by applicant Current seasonal Influenza vaccines are proving to be ineffective especially in at risk populations For example this yearandapos s inactivated flu vaccine had only a efficacy rate against H N infections in the elderly and the current live attenuated Influenza vaccine LAIV is aged restricted for those above years of age Therefore there is glaring un ...

DESCRIPTION provided by applicant This SBIR Phase I proposal is intended to demonstrate the feasibility of developing a novel and effective therapeutic agent for acute radiation injury The threat of nuclear terrorism remains high and there is a possibility of a nuclear power plant leak both of which can cause acute radiation injury at a large scale Currently there are no therapeutic agents ...

DESCRIPTION provided by applicant Hematopoietic stem cell transplantation is a form of stem cell therapy used to treat cancers such as lymphoma and leukemia and other blood related diseases However there currently are several drawbacks in the use of bone marrow hematopoietic cell transplantation Most importantly the donor pool is limited by the need for at least partial HLA matching and t ...

DESCRIPTION provided by applicant Genetic or pharmacologic inhibition of ceramide mediated cell death within the vascular endothelium of the gastrointestinal tract GI protects mice from death from the Radiation GI Syndrome RGS Prophylactic administration of anti ceramide antibody attenuates endothelial apoptosis resulting in significant protection of intestinal stem cells and animal survi ...

DESCRIPTION provided by applicant The goal of this project is address a large unmet medical need by providing more kidneys for transplant For the andgt patients with end stage renal disease in the U S the pool of cadaveric kidneys has remained stagnant over the past decade As a result the dialysis population is expected to reach andgt million patients in the next decade at an aggr ...

DESCRIPTION provided by applicant The ultimate objective of this program is to develop a novel therapeutic approach that will save lives of patients with stroke Acute stroke is the third leading cause of death in the United States and the primary medical cause of acquired adult disability Each year Americans experience new or recurrent stroke It accounts for out of every death ...

DESCRIPTION provided by applicant ELIA Life Technology Inc ELT aims to develop a low cost tactile printer the TouchPrinter which can produce raised text graphics and labels The TouchPrinter serves members of the community of people who are blind or have a visual impairment B VI including caretakers educators and users who are B VI as the output can be read both by touch and sight ...

DESCRIPTION provided by applicant According to the American Cancer Society the best way to lower the risk of non melanoma skin cancer is andquot to practice sun safetyandquot by applying broad spectrum sunscreens A major limitation of commercial Ultraviolet UV filters is that they lack affinity with human skin and are easily removed by water perspiration and normal wear Consequently th ...