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The Award database is continually updated throughout the year. As a result, data for the given year is not complete until April of the following year. Annual Reports data is a snapshot of agency reported information for that year and hence might look different from the live data in the Awards Information charts.

  1. DEVELOPMENT A SPEECH AID TO REHABILITATE LARYNGECTOMEES

    SBC: American Artificial Larynx Com            Topic: N/A

    THIS PROJECT IS PART OF A LONGER TERM EFFORT TO DEVELOP A COMMERCIAL PRODUCT TO ALLOW LARYNGECTOMEES TO REGAIN FULLY NATURAL SPEECH WITH THE SHORTEST REHABILITATION TIME. THE EFFORT TO DATE HAS PRODUCED HARDWARE REPLICATING THE LARYNX FUNCTION IN SPEECH WITH A GOOD QUALITY OF NATURALNESS. THIS PROJECT WILL DETERMINE THE FEASIBILITY OF IMPROVING THE LARYNGECTOMEE'S CONTROL OF THE NEW ARTIFICIAL LAR ...

    SBIR Phase I 1991 Department of Health and Human Services
  2. ELECTROSPRAY TANDEM TIME-OF-FLIGHT MASS SPECTROMETER

    SBC: ANALYTICA OF BRANFORD, INC.            Topic: N/A

    THE OVERALL OBJECTIVE OF THIS RESEARCH IS TO CONTINUE TO IMPROVE ELECTROSPRAY IONIZATION MASS SPECTROMETRY (ESPI-MS) FOR THE ANALYSIS OF BIOLOGICAL MACROMOLECULES. AS A METHOD CAPABLE OF DELIVERING EXTREMELY LARGE MOLECULES INTO THE GAS PHASE AS INTACT DESOLVATED MOLECULAR IONIC SPECIES FROM THEIR POLAR SOLVENTS, ESPI-MS HAS BEEN EFFECTIVELY EXPLOITEDIN DETERMINING THE MOLECULAR WEIGHTS OF PEPTIDE ...

    SBIR Phase II 1991 Department of Health and Human Services
  3. ELECTROSPRAY WITH MECHANICAL VIBRATION ASSIST

    SBC: ANALYTICA OF BRANFORD, INC.            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  4. NOVEL VASCULAR PROSTHETIC DEVICE

    SBC: Bio Med Sciences Inc            Topic: N/A

    THE OBJECTIVE OF THIS RESEARCH PROJECT IS TO DEMONSTRATE THE FEASIBILITY OF UTILIZING A NEWLY DEVELOPED MICROPOROUS MATERIAL FOR VASCULAR PROSTHETIC APPLICATIONS, AND ALSO TO STUDY THE VARIOUS PROCESS PARAMETERS AND THEIR EFFECT ON THE PHYSICAL PROPERTIES OF THE END PRODUCT. AN INTERPENETRATING POLYMER NETWORK ("IPN") OF POLYTETRAFLUOROETHYLENE ("PTFE") AND POLYDIMETHYLSILOXANE ("PDMS") IS EXPANDE ...

    SBIR Phase I 1991 Department of Health and Human Services
  5. COUPLED AMPLIFICATION AND SEQUENCING OF DNA

    SBC: Genaissance Pharmaceuticals            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  6. PROTEIN C PURIFICATION USING AQUEOUS TWO-PHASE SYSTEMS

    SBC: Biphasics Inc            Topic: N/A

    THE OBJECTIVE OF THIS PROGRAM WILL BE TO USE AQUEOUS POLYMER TWO-PHASE SYSTEMS FOR THE PURIFICATION OF PROTEIN C FROM HUMAN PLASMA. BOTH PHASES CONTAIN GREATER THAN 80 PERCENT WATER WITH THE UPPER PHASE RICH IN POLYETHYLENE GLYCOL (PEG) AND THE LOWER PHASE RICH IN A POLYMER OR SALT. THE EXPERIMENTAL PROCEDURE WILL BE AIMED AT EXTRACTING PROTEIN C INTO THE TOP PHASE OF AN AQUEOUS TWO-PHASE SYSTEM T ...

    SBIR Phase I 1991 Department of Health and Human Services
  7. NONLINEAR CARDIOVASCULAR DYNAMICS OF AGING

    SBC: Steven M. Pincus            Topic: N/A

    N/A

    SBIR Phase I 1991 Department of Health and Human Services
  8. PROTEIN PURIFICATION KNOWLEDGE BASE

    SBC: Coact Technologies            Topic: N/A

    RECENT ADVANCES IN BIOTECHNOLOGY AND MOLECULAR BIOLOGY HAVE BROUGHT ABOUT NEW CONCERNS IN PROTEIN PURIFICATION. THE PROTEIN PURIFICATION KNOWLEDGE BASE ADDRESSES SOME OF THESE ISSUES BY PROVIDING NEW COMPUTER-READABLE PROTEIN PURIFICATION DATABASES COUPLED WITH AN EXPERT SYSTEM TO SUGGEST PROTOCOLS FOR PURIFYING NEW PROTEINS. EXPERIMENTAL DATA WILL BE SCANNED, DIGITIZED, AND ANALYZED FOR RELEVANT ...

    SBIR Phase II 1991 Department of Health and Human Services
  9. DEVELOPMENT OF AN EMPLOYEE ASSISTANCE PROGRAM HANDBOOK

    SBC: Consad Research Corp.            Topic: N/A

    THE OBJECTIVE OF THIS RESEARCH IS TO DEVELOP A MANUAL FOR THOSE CONSIDERING IMPLEMENTING EMPLOYEE ASSISTANCE PROGRAMS IN THEIR BUSINESS SETTINGS AS WELL AS FOR THOSE INTERESTED IN IMPROVING, EXPANDING, AND/OR EVALUATING EXISTING EAPS. THE SEVERAL PURPOSES OF THE HANDBOOK OF THIS EFFORT WOULD BE: TO EDUCATE BOTH LARGE AND SMALL BUSINESSES ABOUT THE CONCEPT OF EMPLOYEE ASSISTANCE; TO ACQUAINT POTENT ...

    SBIR Phase II 1991 Department of Health and Human Services
  10. COMPUTER-ASSISTED STEREOTAXIC NEUROSURGICAL SYSTEM

    SBC: Corpitechs Inc.            Topic: N/A

    THIS PROJECT WILL DEVELOP A SYSTEM OF COMPUTER SOFTWARE AND HARDWARE BROADLY APPLICABLE TO PROBLEMS OF STEREOTAXIC NEUROSURGERY. A NEUROSURGICAL WORKSTATION WOULD PROVIDE THESURGEON WITH EASY ACCESS TO DATA FROM DIFFERING IMAGE MODALITIES (E.G., CT, MRI, AND PET) TO OPTIMIZE STEREOTAXIC PROCEDURES. IN CONTRAST TO EXISTING SYSTEMS, THE WORKSTATION WOULD EASILY INTEGRATE MULTIPLE IMAGES IN A COMMON ...

    SBIR Phase II 1991 Department of Health and Human Services

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