Award Data

THIS PROJECT IS PART OF A LONGER TERM EFFORT TO DEVELOP A COMMERCIAL PRODUCT TO ALLOW LARYNGECTOMEES TO REGAIN FULLY NATURAL SPEECH WITH THE SHORTEST REHABILITATION TIME. THE EFFORT TO DATE HAS PRODUCED HARDWARE REPLICATING THE LARYNX FUNCTION IN SPEECH WITH A GOOD QUALITY OF NATURALNESS. THIS PROJECT WILL DETERMINE THE FEASIBILITY OF IMPROVING THE LARYNGECTOMEE'S CONTROL OF THE NEW ARTIFICIAL LAR ...

THE OVERALL OBJECTIVE OF THIS RESEARCH IS TO CONTINUE TO IMPROVE ELECTROSPRAY IONIZATION MASS SPECTROMETRY (ESPI-MS) FOR THE ANALYSIS OF BIOLOGICAL MACROMOLECULES. AS A METHOD CAPABLE OF DELIVERING EXTREMELY LARGE MOLECULES INTO THE GAS PHASE AS INTACT DESOLVATED MOLECULAR IONIC SPECIES FROM THEIR POLAR SOLVENTS, ESPI-MS HAS BEEN EFFECTIVELY EXPLOITEDIN DETERMINING THE MOLECULAR WEIGHTS OF PEPTIDE ...

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THE OBJECTIVE OF THIS RESEARCH PROJECT IS TO DEMONSTRATE THE FEASIBILITY OF UTILIZING A NEWLY DEVELOPED MICROPOROUS MATERIAL FOR VASCULAR PROSTHETIC APPLICATIONS, AND ALSO TO STUDY THE VARIOUS PROCESS PARAMETERS AND THEIR EFFECT ON THE PHYSICAL PROPERTIES OF THE END PRODUCT. AN INTERPENETRATING POLYMER NETWORK ("IPN") OF POLYTETRAFLUOROETHYLENE ("PTFE") AND POLYDIMETHYLSILOXANE ("PDMS") IS EXPANDE ...

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THE OBJECTIVE OF THIS PROGRAM WILL BE TO USE AQUEOUS POLYMER TWO-PHASE SYSTEMS FOR THE PURIFICATION OF PROTEIN C FROM HUMAN PLASMA. BOTH PHASES CONTAIN GREATER THAN 80 PERCENT WATER WITH THE UPPER PHASE RICH IN POLYETHYLENE GLYCOL (PEG) AND THE LOWER PHASE RICH IN A POLYMER OR SALT. THE EXPERIMENTAL PROCEDURE WILL BE AIMED AT EXTRACTING PROTEIN C INTO THE TOP PHASE OF AN AQUEOUS TWO-PHASE SYSTEM T ...

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THIS PHASE I PROJECT WILL RESEARCH THE PROBLEMS THAT TRIBES ENCOUNTER IN THEIR EFFORTS TO SECURE FINANCING FROM INVESTMENT BANKS AND OTHER PRIVATE SECTOR FINANCIAL RESOURCES AND CONSIDER MEASURES TRIBES MIGHT TAKE TO REMEDY THOSE PROBLEMS. IN ADDITION, THIS PHASE I EFFORT WILL RESEARCH AND IDENTIFY PRIVATE SECTOR FINANCIAL RESOURCES TRIBES MIGHT DRAW UPON FOR THEIR DEVELOPMENT NEEDS, THE PERCEPTIO ...

RECENT ADVANCES IN BIOTECHNOLOGY AND MOLECULAR BIOLOGY HAVE BROUGHT ABOUT NEW CONCERNS IN PROTEIN PURIFICATION. THE PROTEIN PURIFICATION KNOWLEDGE BASE ADDRESSES SOME OF THESE ISSUES BY PROVIDING NEW COMPUTER-READABLE PROTEIN PURIFICATION DATABASES COUPLED WITH AN EXPERT SYSTEM TO SUGGEST PROTOCOLS FOR PURIFYING NEW PROTEINS. EXPERIMENTAL DATA WILL BE SCANNED, DIGITIZED, AND ANALYZED FOR RELEVANT ...

THE OBJECTIVE OF THIS RESEARCH IS TO DEVELOP A MANUAL FOR THOSE CONSIDERING IMPLEMENTING EMPLOYEE ASSISTANCE PROGRAMS IN THEIR BUSINESS SETTINGS AS WELL AS FOR THOSE INTERESTED IN IMPROVING, EXPANDING, AND/OR EVALUATING EXISTING EAPS. THE SEVERAL PURPOSES OF THE HANDBOOK OF THIS EFFORT WOULD BE: TO EDUCATE BOTH LARGE AND SMALL BUSINESSES ABOUT THE CONCEPT OF EMPLOYEE ASSISTANCE; TO ACQUAINT POTENT ...