Award Data

The purpose of the present effort is to provide a capability to the Joint Standard Instrumentation Suite (JSIS) for the characterization of ultraviolet atmospheric scattering in order to better determine the impact of atmospheric absorption/scattering on missile signatures.A working prototype of the Characterization of Off-axis Direct and Ultraviolet Scatter (CODUS) instrument will be built and de ...

Project Summary We propose a two-arm adaptive Phase II clinical trial to evaluate ONC201, a selective antagonist of the G protein-coupled receptor (GPCR) dopamine receptor domain 2 (DRD2), in recurrent glioblastoma (GBM) and diffuse midline glioma associated with very poor prognoses and limited treatment options. DRD2 is overexpressed in high grade gliomas and controls Akt/ERK signaling pathways. ...

There is an urgent need for more effective drug delivery agents for treatment of brain tumors, which are among the most aggressive and intractable cancers. SapC-DOPS, a nanovesicle composed of saposin C (SapC) coupled to dioleoylphosphatidylserine (DOPS), has proven tumor targeting properties, which include crossing the blood-brain tumor barrier and binding the lipid tumor marker, extracellular ph ...

A technical data package and Source Approval Request (SAR) will be developed for the manufacturing of the MK 2 Nose Gear Launch Shaft Assembly, NAVAIR part number 511224-1; Shaft, Shouldered, NSN 3040-00-224-9019. The successful SAR submission and approval will result in an additional approved source of supply for DLA for the MK 2 Nose Gear Launch Shaft Assembly, NAVAIR part number 511224-1; Shaf ...

A technical data package and Source Approval Request (SAR) will be developed for the manufacturing of the MK7 Arresting Gear Sheave Assembly, NAVAIR part number 517789-7; Pulley, Groove, NSN 3020-01-560-8493. The successful SAR submission and approval will result in an additional approved source of supply for DLA for the MK7 Arresting Gear Sheave Assembly, NAVAIR part number 517789-7; Pulley, Gro ...

This proposal introduces an approach from Brighton Cromwell to Improve product availability and increase competition through the development of Small Business eligible manufacturing utilizing the DLAs Land and Maritime (L&M) Limited Source National Stock Number (NSN) List. The list contains NSNs with an Annual Demand Value (ADV) >$10K currently sourced with only 1-2 manufacturers. We are offering ...

This proposal introduces an approach from Brighton Cromwell to Improve product availability and increase competition through the development of Small Business eligible manufacturing utilizing the DLAs Land and Maritime (L&M) Limited Source National Stock Number (NSN) List. The list contains NSNs with an Annual Demand Value (ADV) >$10K currently sourced with only 1-2 manufacturers. We are offering ...

This proposal introduces an approach from Brighton Cromwell to Improve product availability and increase competition through the development of Small Business eligible manufacturing utilizing the DLAs Land and Maritime (L&M) Limited Source National Stock Number (NSN) List. The list contains NSNs with an Annual Demand Value (ADV) >$10K currently sourced with only 1-2 manufacturers. We are offering ...

This proposal introduces an approach from Brighton Cromwell to Improve product availability and increase competition through the development of Small Business eligible manufacturing utilizing the DLAs Land and Maritime (L&M) Limited Source National Stock Number (NSN) List. The list contains NSNs with an Annual Demand Value (ADV) >$10K currently sourced with only 1-2 manufacturers. We are offering ...

Parts Life Incorporated (PLI) will utilize it's proven SAR Process and Reverse Engineering Risk Avoidance Process (RERAP) to demonstrate its ability to cut the cost of the Seal Asy Hub, 2530-00-736-4672 by 20% through efficiency and quality management programs. The DLA will save over $200,000 in annual cost for procurement of the Seal by utilizing PLI's method of manufacturing. Parts Life In ...