Award Data

DESCRIPTION (provided by applicant): A closed loop, glucose sensing, and insulin responsive system could dramatically improve treatment options for insulin dependent diabetics. Current artificial systems, however, lack the ability to provide this precise control. Clinical islet transplantation, the intrahepatic loading of allogeneic islets, shows the potential to provide this intimate control, by ...

Anaerobic digesters are capable of producing methane-rich biogas from animal manure and also offer the advantages of controlling odors, reducing pathogens, and minimizing the environmental impact of the waste. The biogas produced from anaerobic digesters is a renewable, distributed source of energy that can be used to generate electricity to offset power consumption on farms. Unfortunately, biogas ...

Anaerobic digesters are capable of producing methane-rich biogas from animal manure and also offer the advantages of controlling odors, reducing pathogens, and minimizing the environmental impact of the waste. The biogas produced from anaerobic digesters is a renewable, distributed source of energy that can be used to generate electricity to offset power consumption on farms. Unfortunately, biogas ...

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DESCRIPTION (provided by applicant): Principal Investigator/Program Director (Last, First, Middle): Abstract We propose to design and deploy a handheld breath-based "personal" medication adherence monitoring system (MAMS) which will meet the criteria of the solicitation from the National Institute of Mental Health (NIMH) for "Development of information, instruments or methodologies to improve and/ ...

DESCRIPTION (provided by applicant): Building on our Phase I achievements, we will design and deploy a handheld, breath-based medication adherence monitoring system (adherence system) to identify adherence for clinical trials. The system consists of a miniature, battery powered gas chromatograph (the device) capable of measuring volatile metabolites (e.g., butanone) on an individual's breath after ...

DESCRIPTION (provided by applicant): Addiction annually costs America gt 500B. Narcotic addiction is especially worrisome since intravenous drug abuse (IVDA) also promotes HIV transmission. Reducing IVDA is critical to lowering the incidence of HIV. Sincegt75% of IVDA is with opioids, effective treatment of opiate addiction should markedly reduce IVDA and lower HIV transmission rates. Naltrexone ...

Thousands of canines are on active duty/deployed at any given time, protecting their human partners from threats and attacks. When MWDs are injured in austere/remote locations, professional veterinary care is often unavailable. Non-veterinary healthcare providers are expected to provide lifesaving care until higher-level veterinary care can be reached. A significant gap exists in canine training a ...

ABSTRACT: When a structure breaks up following a blast event, it allows the blast wave to propagate through a new opening into another airspace; this continuation of the blast wave is called"secondary blast"and may cause damage to elements in the other airspace. Each step in this process is a candidate for some type of acceleration. Current assessment codes incorporate several Fast Running Model ...

The development of a burn-in process for high power MWIR and LWIR Quantum Cascade Lasers (QCLs) is proposed. The new burn-in process will be rooted in extensive statistical experimental data to be collected in Phase I and Phase II of this program. This will allow us to extract all the critical empirical parameters required for mean-time-to-failure (MTTF) projections for high power MWIR and LWIR de ...